Evidence map›Paper›PMID 41614887›Full record

ArticleCurrent issues in molecular biology2026

Multi-Target Anticancer Activity of Structurally Diverse Schiff Bases: Insights into Cell-Cycle Arrest, DNA Damage, Metabolic Signaling, and Biomolecular Binding.

Nenad Joksimović, Jelena Petronijević, Ignjat Filipović, Nenad Janković, Bojana Ilić, Tatjana Stanojković, Ana Djurić

Abstract read
In one paragraph

Article in Current issues in molecular biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Nenad JoksimovićDepartment of Chemistry, Faculty of Science, University of Kragujevac, Radoja Domanovića 12, 34000 Kragujevac, Serbia.ORCID 0000-0003-3365-6762
Jelena PetronijevićDepartment of Chemistry, Faculty of Science, University of Kragujevac, Radoja Domanovića 12, 34000 Kragujevac, Serbia.ORCID 0000-0003-3427-5427
Ignjat FilipovićDepartment of Chemistry, Faculty of Science, University of Kragujevac, Radoja Domanovića 12, 34000 Kragujevac, Serbia.
Nenad JankovićDepartment of Sciences, Institute for Information Technologies Kragujevac, University of Kragujevac, Jovana Cvijića bb, 34000 Kragujevac, Serbia.ORCID 0000-0002-2295-9410
Bojana IlićClinic for Endocrinology, Diabetes and Metabolic Diseases, University Clinical Centre of Serbia, 11000 Belgrade, Serbia.
Tatjana StanojkovićInstitute of Oncology and Radiology of Serbia, Pasterova 14, 11000 Belgrade, Serbia.
Ana DjurićClinic for Endocrinology, Diabetes and Metabolic Diseases, University Clinical Centre of Serbia, 11000 Belgrade, Serbia.ORCID 0000-0002-4440-9890

Funding

Ministry of Education, Science and Technological Development of the Republic of Serbia Agreements No. 451-03-136/ 2025-03/200122 and Project No. III41010451-03-68/2022-14/ 200043
6 · The paper itself

Abstract

Schiff bases are widely studied for their biological activities, yet structure-activity relationships governing their anticancer potential remain insufficiently understood. In this work, eight structurally diverse imine derivatives (

Indexed as

anticancer activitybovine serum albumincell cycle arrestDNA damageHIF-1αmolecular dockingPDK3ROS modulationSchiff bases

Identifiers

PMID41614887
PMCPMC12840311

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.