Evidence map›Paper›PMID 41614740›Full record

ReviewCurrent issues in molecular biology2025

A Review of Differential Plant Responses to Drought, Heat, and Combined Drought + Heat Stress.

Nankai Li, Zhi Geng, Xiaodong Huang, Shunqi Huang, Lulu Song, Ruirui Chen, Ziping Chen, Liji Du, Congshan Xu

Abstract readReview
In one paragraph

Review in Current issues in molecular biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Nankai LiAnhui Science and Technology Achievement Transformation Promotion Center, Anhui Provincial Institute of Science and Technology, Hefei 230031, China.
Zhi GengCollege of Agronomy, Nanjing Agricultural University, Nanjing 210014, China.
Xiaodong HuangAnhui Science and Technology Achievement Transformation Promotion Center, Anhui Provincial Institute of Science and Technology, Hefei 230031, China.
Shunqi HuangAnhui Science and Technology Achievement Transformation Promotion Center, Anhui Provincial Institute of Science and Technology, Hefei 230031, China.
Lulu SongAnhui Science and Technology Achievement Transformation Promotion Center, Anhui Provincial Institute of Science and Technology, Hefei 230031, China.
Ruirui ChenAnhui Science and Technology Achievement Transformation Promotion Center, Anhui Provincial Institute of Science and Technology, Hefei 230031, China.
Ziping ChenAnhui Science and Technology Achievement Transformation Promotion Center, Anhui Provincial Institute of Science and Technology, Hefei 230031, China.
Liji DuAnhui Science and Technology Achievement Transformation Promotion Center, Anhui Provincial Institute of Science and Technology, Hefei 230031, China.
Congshan XuAnhui Science and Technology Achievement Transformation Promotion Center, Anhui Provincial Institute of Science and Technology, Hefei 230031, China.ORCID 0000-0003-0104-6046

Funding

a grant funded by Hefei Lvbao Seedling Company Contract No. lg24448National Key Research and Development Program Project (2023YFE0110100
6 · The paper itself

Abstract

Global warming increases the frequency with which drought and heat stress occur simultaneously, especially in semi-arid regions. Such combined stress imposes a non-additive and more severe impact on plant growth, yield, and quality than either stress alone. Here, we integrate recent physiological, biochemical, and multi-omics studies to compare individual and combined stress responses and to dissect the underlying signal transduction networks. We show that drought-dominated phases rapidly elevate ABA concentrations and activate SnRK2-AREB cascades, whereas heat pulses trigger jasmonic acid and ethylene signals that antagonize ABA-driven stomatal closure. Under combined stress, these hormonal modules converge on a "competitive TF marketplace", where ABA, JA, and GA cis-elements co-regulate invertase-sugar checkpoints, heat shock factor/ROS oscillators, and chromatin-remodeling events that determine reproductive fate. Recent advances using multi-omics approaches and systems biology have further elucidated these complex networks. These insights will inform future breeding strategies aiming to develop stress-tolerant crops. We highlight emerging tools-weighted gene co-expression networks, kinetic multi-omics, and cis-regulatory CRISPR editing-that can exploit these signaling hubs for breeding crops with improved combined stress tolerance.

Indexed as

biochemical regulationcombined stressdrought stressheat stressmolecular mechanismsphysiological responsesignal transduction

Identifiers

PMID41614740
PMCPMC12732293

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.