Evidence map›Paper›PMID 41614641›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2026

Intelligent Thermo-Self-Limited Magnetothermia with Heat-Triggered TERT Silencing for Precision Synergetic Cancer Therapy.

Liang Zhang, Mingfu Gong, Tao Sun, Shilin Xiao, Yue Zhao, Xiaofeng Yang, Wansu Zhang, Chunyu Zhou, Xu Liu, Dong Zhang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Liang ZhangDepartment of Radiology, Xinqiao Hospital, Army Medical University, Chongqing, P. R. China.ORCID https://orcid.org/0000-0002-8514-5123
Mingfu GongDepartment of Radiology, Xinqiao Hospital, Army Medical University, Chongqing, P. R. China.
Tao SunDepartment of Radiology, Xinqiao Hospital, Army Medical University, Chongqing, P. R. China.
Shilin XiaoDepartment of Radiology, Xinqiao Hospital, Army Medical University, Chongqing, P. R. China.
Yue ZhaoDepartment of Radiology, Xinqiao Hospital, Army Medical University, Chongqing, P. R. China.
Xiaofeng YangDepartment of Radiology, Xinqiao Hospital, Army Medical University, Chongqing, P. R. China.
Wansu ZhangDepartment of Radiology, Xinqiao Hospital, Army Medical University, Chongqing, P. R. China.
Chunyu ZhouDepartment of Radiology, Xinqiao Hospital, Army Medical University, Chongqing, P. R. China.
Xu LiuDepartment of Radiology, Xinqiao Hospital, Army Medical University, Chongqing, P. R. China.
Dong ZhangDepartment of Radiology, Xinqiao Hospital, Army Medical University, Chongqing, P. R. China.ORCID https://orcid.org/0000-0003-0332-1195

Funding

Chongqing Young and Middle-aged Medical High-end Talent projectNational Natural Science Foundation of China 32301196National Natural Science Foundation of China 82372030Natural Science Foundation of Chongqing CSTB2025NSCQ-GPX0587Natural Science Foundation of Chongqing CSTB2025NSCQ-GPX0603Young Doctoral Talent Incubation project of the Second Affiliated Hospital of Army Medical University 2023YQB034
6 · The paper itself

Abstract

The combination of hyperthermal therapy and gene therapy (GT) has emerged as a promising strategy for cancer treatment. However, the overheating damage and complex temperature control procedure in hyperthermal therapy, along with the limited precision of GT, greatly compromise the therapeutic effectiveness. In this study, a novel nanoplatform (IONP@H

Indexed as

Genetic TherapyHyperthermia, InducedNeoplasmsTelomeraseAnimalsCell Line, TumorGene SilencingHot TemperatureHumansMiceTelomeraseTERT protein, humanHsp70 promoterin situ siRNA synthesisself‐limited thermalsynergetic cancer therapyultra‐small iron oxide nanoparticles

Identifiers

PMID41614641
PMCPMC13067769

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.