Evidence map›Paper›PMID 41614497›Full record

Observational studyEuropean stroke journal2026

Thrombectomy with and without emergent stenting in acute ischemic stroke due to carotid artery dissection.

Lisa Kaindl, Michail Giannakakis, Joshua Mbroh, Alexandra Gomez Exposito, Stefan Krebs, Julian Hotz, Dominika Miksova, Mira Katan, Susanne Wegener, Marco De Marchis Gian and 17 more

Erratum issuedAbstract readMulticenter StudyObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in European stroke journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

27 authors.

Lisa KaindlDepartment of Neurology, St. John's Hospital Vienna, Vienna, Austria.
Michail GiannakakisDepartment of Neurology, University Hospital and University Basel, Basel, Switzerland.
Joshua MbrohDepartment of Neurology & Stroke, University of Tübingen, Tübingen, Germany.
Alexandra Gomez ExpositoDepartment of Neurology & Stroke, University of Tübingen, Tübingen, Germany.
Stefan KrebsDepartment of Neurology, St. John's Hospital Vienna, Vienna, Austria.
Julian HotzDepartment of Neurology, St. John's Hospital Vienna, Vienna, Austria.
Dominika MiksovaGesundheit Österreich GmbH, Vienna, Austria.
Mira KatanDepartment of Neurology, University Hospital and University Basel, Basel, Switzerland.
Susanne WegenerDepartment of Neurology, Universitätsspital Zürich, Zürich, Switzerland.ORCID 0000-0003-4369-7023
Marco De Marchis GianDepartment of Neurology, University Teaching & Research Hospital, HOCH Cantonal Hospital St. Gallen, St. Gallen, Switzerland.
Thomas GattringerDepartment of Neurology, Medical University Graz, Graz, Austria.
Hannes DeutschmannDivision of Neuroradiology, Vascular and Interventional Radiology, Department of Radiology, Medical University Graz, Graz, Austria.
Lukas Mayer-SuessDepartment of Neurology, Medical University Innsbruck, Innsbruck, Austria.
Jens FiehlerDepartment of Neuroradiology, University Hamburg, Hamburg, Germany.
Ulrike ErnemannDepartment of Neuroradiology, University Tübingen, Tübingen, Germany.
Florian HennersdorfDepartment of Neuroradiology, University Hamburg, Hamburg, Germany.
Urs FischerDepartment of Neurology, University Hospital Bern, University of Bern, Bern, Switzerland.
Zsolt KulcsarDepartment of Neuroradiology, Clinical Neuroscience Center, University Hospital of Zürich, Zürich, Switzerland.
Pasquale MordasiniInstitute of Diagnostic and Interventional Neuroradiology, Kantonsspital Aarau (KSA), Aarau, Switzerland.
Marios-Nikos PsychogiosDepartment of Neuroradiology, University Basel, Basel, Switzerland.
Ruth Gizewski ElkeDepartment of Radiology, Medical University Innsbruck, Innsbruck, Austria.
Christian NolteDepartment of Neurology with Experimental Neurology, Charité Universitätsmedizin Berlin and Center for Stroke Research (CSB), Berlin, Germany.
Christian NeumannDepartment of Radiology, St. John's Hospital Vienna, Vienna, Austria.
Julia FerrariDepartment of Neurology, St. John's Hospital Vienna, Vienna, Austria.
Tomas DobrockyDepartment of Neuroradiology, University Hospital Bern, Bern, Switzerland.
Sven PoliDepartment of Neurology & Stroke, University of Tübingen, Tübingen, Germany.
Marek SykoraDepartment of Neurology, St. John's Hospital Vienna, Vienna, Austria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionWhether thrombectomy with or without emergent carotid stenting improves outcomes in patients with large vessel occlusion (LVO) stroke due to carotid artery dissection (CAD) is unknown. PATIENTS AND

methodsInternational multicentre observational study. Patients with LVO due to CAD undergoing thrombectomy with emergent stenting were compared to those without emergent stenting. The primary outcome was functional independence (modified Rankin Scale 0-2) at 3 months, secondary outcomes included early neurological improvement (ENI) within 24-48 h, successful recanalisation, symptomatic intracerebral haemorrhage (sICH) and mortality at 3 months. Inverse probability of treatment weighting and multivariable Poisson regression were used to adjust for group imbalances and to estimate the effect size, respectively.

resultsOf 516 patients (mean age 53.8 years, 76% male) undergoing thrombectomy, 167 (32.4%) and 349 (67.6%) were treated with or without emergent carotid stenting, respectively. After robust adjustment, emergent stenting was not associated with functional independence (adjusted risk ratio [aRR] = 1.01; 95% confidence interval [CI], 0.89-1.15) or ENI (aRR = 1.07; 95% CI, 0.95-1.21) but with successful recanalisation (aRR = 1.29; 95% CI, 1.10-1.50) and reduced mortality at 3 months (aRR = 0.39; 95% CI, 0.15-0.99). Risk of sICH was equivalent (aRR = 1.01; 95% CI, 0.95-1.06).

conclusionIn patients with LVO secondary to CAD, emergent stenting during endovascular procedure appeared safe, increased odds of successful recanalisation and reduced 3-month mortality rates. However, intraprocedural stenting was not associated with better functional outcome.

Indexed as

Brain IschemiaCarotid Artery, Internal, DissectionIschemic StrokeStentsThrombectomyAgedFemaleHumansMaleMiddle AgedTreatment Outcomedissectionoutcomestentingstrokethrombectomy

Identifiers

PMID41614497
PMCPMC12866227

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.