Evidence map›Paper›PMID 41614242›Full record

ArticleCirculation. Cardiovascular imaging2026

Prognostic Significance of Noninvasive Simultaneous Renal and Cardiac Perfusion: Interrogating Mechanisms of Cardiovascular-Kidney Interactions.

Omolabake O Alabi, Zhou Lan, Daniel M Huck, Marie Foley Kijewski, Mi-Ae Park, Jon Hainer, Sylvain L Carre, Anna Perillo, Laurel Martell, Leanne Barrett and 8 more

Abstract read
In one paragraph

Article in Circulation. Cardiovascular imaging, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Omolabake O AlabiDepartment of Medicine (O.O.A.), Brigham and Women's Hospital, Harvard Medical School, Boston, MA.ORCID 0000-0002-3131-135X
Zhou LanDepartment of Radiology (Z.L.), Brigham and Women's Hospital, Harvard Medical School, Boston, MA.
Daniel M HuckCardiovascular Imaging Program, Departments of Medicine and Radiology (D.M.H., M.F.K., J.H., S.L.C., A.P., L.M., L.B., B.N.W., S. Divakaran, D.M.L., R.B., S. Dorbala, M.F.D.C., J.M.B.), Brigham and Women's Hospital, Harvard Medical School, Boston, MA.ORCID 0000-0003-4221-8078
Marie Foley KijewskiCardiovascular Imaging Program, Departments of Medicine and Radiology (D.M.H., M.F.K., J.H., S.L.C., A.P., L.M., L.B., B.N.W., S. Divakaran, D.M.L., R.B., S. Dorbala, M.F.D.C., J.M.B.), Brigham and Women's Hospital, Harvard Medical School, Boston, MA.ORCID 0000-0001-8365-1447
Mi-Ae ParkDepartment of Radiology, UT Southwestern Medical Center, Dallas, TX (M.-A.P.).ORCID 0000-0003-0806-129X
Jon HainerCardiovascular Imaging Program, Departments of Medicine and Radiology (D.M.H., M.F.K., J.H., S.L.C., A.P., L.M., L.B., B.N.W., S. Divakaran, D.M.L., R.B., S. Dorbala, M.F.D.C., J.M.B.), Brigham and Women's Hospital, Harvard Medical School, Boston, MA.ORCID 0000-0002-0572-912X
Sylvain L CarreCardiovascular Imaging Program, Departments of Medicine and Radiology (D.M.H., M.F.K., J.H., S.L.C., A.P., L.M., L.B., B.N.W., S. Divakaran, D.M.L., R.B., S. Dorbala, M.F.D.C., J.M.B.), Brigham and Women's Hospital, Harvard Medical School, Boston, MA.
Anna PerilloCardiovascular Imaging Program, Departments of Medicine and Radiology (D.M.H., M.F.K., J.H., S.L.C., A.P., L.M., L.B., B.N.W., S. Divakaran, D.M.L., R.B., S. Dorbala, M.F.D.C., J.M.B.), Brigham and Women's Hospital, Harvard Medical School, Boston, MA.ORCID 0009-0009-0083-2759
Laurel MartellCardiovascular Imaging Program, Departments of Medicine and Radiology (D.M.H., M.F.K., J.H., S.L.C., A.P., L.M., L.B., B.N.W., S. Divakaran, D.M.L., R.B., S. Dorbala, M.F.D.C., J.M.B.), Brigham and Women's Hospital, Harvard Medical School, Boston, MA.ORCID 0009-0008-8735-0674
Leanne BarrettCardiovascular Imaging Program, Departments of Medicine and Radiology (D.M.H., M.F.K., J.H., S.L.C., A.P., L.M., L.B., B.N.W., S. Divakaran, D.M.L., R.B., S. Dorbala, M.F.D.C., J.M.B.), Brigham and Women's Hospital, Harvard Medical School, Boston, MA.ORCID 0000-0003-0667-8720
Brittany N WeberCardiovascular Imaging Program, Departments of Medicine and Radiology (D.M.H., M.F.K., J.H., S.L.C., A.P., L.M., L.B., B.N.W., S. Divakaran, D.M.L., R.B., S. Dorbala, M.F.D.C., J.M.B.), Brigham and Women's Hospital, Harvard Medical School, Boston, MA.ORCID 0000-0002-0177-2091
Sanjay DivakaranCardiovascular Imaging Program, Departments of Medicine and Radiology (D.M.H., M.F.K., J.H., S.L.C., A.P., L.M., L.B., B.N.W., S. Divakaran, D.M.L., R.B., S. Dorbala, M.F.D.C., J.M.B.), Brigham and Women's Hospital, Harvard Medical School, Boston, MA.ORCID 0000-0003-0598-6502
Diana M LopezCardiovascular Imaging Program, Departments of Medicine and Radiology (D.M.H., M.F.K., J.H., S.L.C., A.P., L.M., L.B., B.N.W., S. Divakaran, D.M.L., R.B., S. Dorbala, M.F.D.C., J.M.B.), Brigham and Women's Hospital, Harvard Medical School, Boston, MA.ORCID 0000-0001-6335-9625
Ron BlanksteinCardiovascular Imaging Program, Departments of Medicine and Radiology (D.M.H., M.F.K., J.H., S.L.C., A.P., L.M., L.B., B.N.W., S. Divakaran, D.M.L., R.B., S. Dorbala, M.F.D.C., J.M.B.), Brigham and Women's Hospital, Harvard Medical School, Boston, MA.ORCID 0000-0002-8393-6562
Sharmila DorbalaCardiovascular Imaging Program, Departments of Medicine and Radiology (D.M.H., M.F.K., J.H., S.L.C., A.P., L.M., L.B., B.N.W., S. Divakaran, D.M.L., R.B., S. Dorbala, M.F.D.C., J.M.B.), Brigham and Women's Hospital, Harvard Medical School, Boston, MA.ORCID 0000-0003-1462-1185
Piotr J SlomkaDivision of Artificial Intelligence, Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA (P.J.S.).ORCID 0000-0002-6110-938X
Marcelo F Di CarliCardiovascular Imaging Program, Departments of Medicine and Radiology (D.M.H., M.F.K., J.H., S.L.C., A.P., L.M., L.B., B.N.W., S. Divakaran, D.M.L., R.B., S. Dorbala, M.F.D.C., J.M.B.), Brigham and Women's Hospital, Harvard Medical School, Boston, MA.ORCID 0000-0003-3119-025X
Jenifer M BrownCardiovascular Imaging Program, Departments of Medicine and Radiology (D.M.H., M.F.K., J.H., S.L.C., A.P., L.M., L.B., B.N.W., S. Divakaran, D.M.L., R.B., S. Dorbala, M.F.D.C., J.M.B.), Brigham and Women's Hospital, Harvard Medical School, Boston, MA.ORCID 0000-0002-6647-639X

Funding

Patient-specific Outcome Prediction from Cardiovascular Multimodality Imaging by Artificial IntelligenceR35HL161195 · NHLBI · CEDARS-SINAI MEDICAL CENTER · PI Piotr J Slomka · 2022 to 2026
$5.0M
Mineralocorticoid receptor, coronary microvascular function, and cardiac efficiency in hypertensionR01HL162960 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI Gail Kurr Adler, Marcelo F DI CARLI · 2023 to 2026
$3.1M
Cardiac Perfusion, Structure, and Function across the Primary Aldosteronism SpectrumK23HL159279 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI Jenifer Michelle Brown · 2022 to 2026
$1.0M
Advanced CV imaging and immunophenotyping to study coronary vascular health in psoriasisK23HL159276 · NHLBI · UT SOUTHWESTERN MEDICAL CENTER · PI WEBER, BRITTANY NICOLE · 2021 to 2025
$962k
NHLBI NIH HHS K23 HL159276NHLBI NIH HHS K23 HL159279NHLBI NIH HHS R01 HL162960NHLBI NIH HHS R35 HL161195
6 · The paper itself

Abstract

backgroundPhysiologic interaction between the cardiovascular and renal systems is pivotal in the understanding of disease and as a target for therapeutic interventions, as highlighted in the cardiovascular-kidney-metabolic syndrome. This study explores the association of renal blood flow, derived noninvasively from cardiac positron emission tomography-computed tomography, with cardiovascular and renal outcomes.

methodsWe evaluated the association between renal blood flow and outcomes in a retrospective cohort of 295 consecutive patients who underwent

resultsThe population had a mean age of 65.6 years, a body mass index of 29.2 kg/m

conclusionsImpaired renal blood flow is associated with cardiac and kidney events, independent of the highly prognostic estimated glomerular filtration rate and myocardial flow reserve. Simultaneous quantification of cardiac and renal perfusion by noninvasive

Indexed as

Cardiovascular DiseasesCoronary CirculationMyocardial Perfusion ImagingPositron Emission Tomography Computed TomographyRenal CirculationAgedFemaleGlomerular Filtration RateHumansMaleMiddle AgedPredictive Value of TestsPrognosisRetrospective StudiesRisk Factorscardio-renal syndromekidneymyocardial perfusion imagingpositron emission tomographyprognosis

Identifiers

PMID41614242
PMCPMC12866957

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.