ArticleJACS Au2026
Affinity Maturation of a Fentanyl Aptamer by Motif-SELEX.
Article in JACS Au, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Authors and funding
7 authors.
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No grant is acknowledged in the PubMed record.
Abstract
Oligonucleotide-based aptamers are increasingly being used as recognition elements in biosensors to detect analytes relevant to diverse applications including medical diagnostics and therapeutic drug monitoring. Nevertheless, the utility of aptamers is often hindered by their insufficient target-binding affinity. We recently developed an affinity maturation approach termed Motif-SELEX that can improve aptamer binding affinity by up to an order of magnitude. This approach entails performing
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