Evidence map›Paper›PMID 41614175›Full record

ArticleJACS Au2026

Microwave-Assisted Thioester-Empowered Toolkit for Modular Glycopeptide Synthesis.

Yue Yang, Miaomiao Zhang, Meng-Hai Xiang, Tong Li, Huiran Hao, Yuanyuan Li, Ning Wang, Richard R Schmidt, Hongxiang Lou, Peng Peng and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in JACS Au, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Yue YangNational Glycoengineering Research Center, Shandong Key Laboratory of Carbohydrate and Carbohydrate-conjugate Drugs, Shandong Technology Innovation Center of Carbohydrate, Shandong University, 72 Binhai Road, Qingdao, Shandong 266237, China.
Miaomiao ZhangNational Glycoengineering Research Center, Shandong Key Laboratory of Carbohydrate and Carbohydrate-conjugate Drugs, Shandong Technology Innovation Center of Carbohydrate, Shandong University, 72 Binhai Road, Qingdao, Shandong 266237, China.
Meng-Hai XiangState Key Laboratory of Biopharmaceutical Preparation and Delivery, Institute of Process Engineering, Chinese Academy of Sciences, Beijing 100190, China.
Tong LiNational Glycoengineering Research Center, Shandong Key Laboratory of Carbohydrate and Carbohydrate-conjugate Drugs, Shandong Technology Innovation Center of Carbohydrate, Shandong University, 72 Binhai Road, Qingdao, Shandong 266237, China.
Huiran HaoNational Glycoengineering Research Center, Shandong Key Laboratory of Carbohydrate and Carbohydrate-conjugate Drugs, Shandong Technology Innovation Center of Carbohydrate, Shandong University, 72 Binhai Road, Qingdao, Shandong 266237, China.
Yuanyuan LiNational Glycoengineering Research Center, Shandong Key Laboratory of Carbohydrate and Carbohydrate-conjugate Drugs, Shandong Technology Innovation Center of Carbohydrate, Shandong University, 72 Binhai Road, Qingdao, Shandong 266237, China.
Ning WangState Key Laboratory of Biopharmaceutical Preparation and Delivery, Institute of Process Engineering, Chinese Academy of Sciences, Beijing 100190, China.
Richard R SchmidtDepartment of Chemistry, University of Konstanz, Fach 725, D-78457 Konstanz, Germany.ORCID https://orcid.org/0000-0001-6398-9053
Hongxiang LouNational Glycoengineering Research Center, Shandong Key Laboratory of Carbohydrate and Carbohydrate-conjugate Drugs, Shandong Technology Innovation Center of Carbohydrate, Shandong University, 72 Binhai Road, Qingdao, Shandong 266237, China.ORCID https://orcid.org/0000-0003-3300-1811
Peng PengNational Glycoengineering Research Center, Shandong Key Laboratory of Carbohydrate and Carbohydrate-conjugate Drugs, Shandong Technology Innovation Center of Carbohydrate, Shandong University, 72 Binhai Road, Qingdao, Shandong 266237, China.ORCID https://orcid.org/0000-0003-4625-6610
Tianlu LiNational Glycoengineering Research Center, Shandong Key Laboratory of Carbohydrate and Carbohydrate-conjugate Drugs, Shandong Technology Innovation Center of Carbohydrate, Shandong University, 72 Binhai Road, Qingdao, Shandong 266237, China.ORCID https://orcid.org/0000-0002-0674-3687

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Glycopeptides and glycoproteins with structural precision are valuable for functional studies and applications. Conventional couplings of glycosyl amino acids are slow, wasteful, and impractical for broad use. To address the fundamental synthetic challenges, the current work presents a new paradigm for glycopeptide synthesis, featuring a key component (thioester-functionalized glycosyl amino acid) and a comprehensive reaction system (AgSbF

Indexed as

chemoenzymatic synthesisglycopeptidemicrowavemodular synthesisthioester

Identifiers

PMID41614175
PMCPMC12848699

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.