Supramolecular Zwitterionic Polymers: Dynamic Traits Imparted by Ionic Interactions.

Jin Wang, Xuedong Xiao, Xinghuo Xiao, Jianwei Sun, Ryan T K Kwok, Jacky W Y Lam, Ben Zhong Tang

Abstract readReview

In one paragraph

Review in JACS Au, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jin WangDepartment of Chemistry, Hong Kong Branch of Chinese National Engineering Research Center for Tissue Restoration and Reconstruction, Department of Chemical and Biological Engineering, and State Key Laboratory of Nervous System Disorders, The Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong 999077, China.

Xuedong XiaoDepartment of Chemistry, Hong Kong Branch of Chinese National Engineering Research Center for Tissue Restoration and Reconstruction, Department of Chemical and Biological Engineering, and State Key Laboratory of Nervous System Disorders, The Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong 999077, China.

Xinghuo XiaoDepartment of Chemistry, Hong Kong Branch of Chinese National Engineering Research Center for Tissue Restoration and Reconstruction, Department of Chemical and Biological Engineering, and State Key Laboratory of Nervous System Disorders, The Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong 999077, China.

Jianwei SunDepartment of Chemistry, Hong Kong Branch of Chinese National Engineering Research Center for Tissue Restoration and Reconstruction, Department of Chemical and Biological Engineering, and State Key Laboratory of Nervous System Disorders, The Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong 999077, China.ORCID https://orcid.org/0000-0002-2470-1077

Ryan T K KwokDepartment of Chemistry, Hong Kong Branch of Chinese National Engineering Research Center for Tissue Restoration and Reconstruction, Department of Chemical and Biological Engineering, and State Key Laboratory of Nervous System Disorders, The Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong 999077, China.ORCID https://orcid.org/0000-0002-6866-3877

Jacky W Y LamDepartment of Chemistry, Hong Kong Branch of Chinese National Engineering Research Center for Tissue Restoration and Reconstruction, Department of Chemical and Biological Engineering, and State Key Laboratory of Nervous System Disorders, The Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong 999077, China.

Ben Zhong TangDepartment of Chemistry, Hong Kong Branch of Chinese National Engineering Research Center for Tissue Restoration and Reconstruction, Department of Chemical and Biological Engineering, and State Key Laboratory of Nervous System Disorders, The Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong 999077, China.ORCID https://orcid.org/0000-0002-0293-964X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Supramolecular ionic polymers (SIPs) exhibit distinctive dynamic properties, which arise from the synergistic combination of substantial strength and pronounced reversibility of ionic interactions. However, conventional SIPs formed by coassembly using anionic and cationic separated double monomers suffer from complicated synthesis and heterogeneous structures, which obscure in-depth investigation of their dynamic behaviors. In response, we developed a zwitterionic monomer, namely TPE-2N2S, that incorporates both charged motifs into one fluorescent tetraphenylethylene (TPE) skeleton. This zwitterionic and single-component monomer design strategy enables the efficient formation of supramolecular zwitterionic polymers (SZIPs) with a uniform and orderly structure, and it can further enhance the understanding of structure-property relationships. In this perspective, we examine the dynamic features of ionic interactions in SZIPs, emphasizing their structural advantages, controllable assembly, and ionic interaction characteristics. We further investigate the dynamic behavior driven by ionic interactions at the intramolecular, intermolecular, and supramolecular architecture levels. Finally, we discuss key challenges and future opportunities in this emerging field, aiming to advance the design and application of SZIPs.

Indexed as

dynamic transitionionic aggregatesionic interactionsstimuli-responsivesupramolecular zwitterionic polymers

Identifiers

PMID41614169

DOI10.1021/jacsau.5c01400

PMCPMC12848712

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