Evidence map›Paper›PMID 41614160›Full record

ArticleJACS Au2026

Sequential Regiodivergent Polyol Sulfonylation and Functionalization Enable Precise Engineering of Carbohydrates.

Siai Zhou, Cai Huang, Aoxin Guo, Han Ding, Jiawei Li, Lan Ye, Guangkai Bian, Xue-Wei Liu, Feiqing Ding, Hui Cai

Abstract read
In one paragraph

Article in JACS Au, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Siai ZhouSchool of Pharmaceutical Sciences (Shenzhen), Shenzhen Campus of Sun Yat-sen University, Shenzhen 518107, China.
Cai HuangSchool of Pharmaceutical Sciences (Shenzhen), Shenzhen Campus of Sun Yat-sen University, Shenzhen 518107, China.
Aoxin GuoSchool of Chemistry, Chemical Engineering and Biotechnology, Nanyang Technological University, Singapore 637371, Singapore.
Han DingSchool of Chemistry, Chemical Engineering and Biotechnology, Nanyang Technological University, Singapore 637371, Singapore.ORCID https://orcid.org/0000-0003-3170-0723
Jiawei LiSchool of Pharmaceutical Sciences (Shenzhen), Shenzhen Campus of Sun Yat-sen University, Shenzhen 518107, China.
Lan YeSchool of Pharmaceutical Sciences (Shenzhen), Shenzhen Campus of Sun Yat-sen University, Shenzhen 518107, China.
Guangkai BianCenter of Materials Synthetic Biology, State Key Laboratory of Quantitative Engineering Biology, Shenzhen Institute of Synthetic Biology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China.
Xue-Wei LiuSchool of Chemistry, Chemical Engineering and Biotechnology, Nanyang Technological University, Singapore 637371, Singapore.ORCID https://orcid.org/0000-0002-8327-6664
Feiqing DingSchool of Pharmaceutical Sciences (Shenzhen), Shenzhen Campus of Sun Yat-sen University, Shenzhen 518107, China.ORCID https://orcid.org/0000-0002-0211-7101
Hui CaiSchool of Pharmaceutical Sciences (Shenzhen), Shenzhen Campus of Sun Yat-sen University, Shenzhen 518107, China.ORCID https://orcid.org/0000-0002-5394-8167

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Substituent functionalization of unprotected and partially protected carbohydrates with controlled regioselectivity remains challenging due to the difficulty in differentiating hydroxyl groups with similar reactivities. This study presents an efficient protocol for site-specific modification through a "two-stage," regiodivergent polyol tagging and functionalization strategy. To achieve effective tagging, we developed two complementary Ag

Indexed as

[Ag] catalystaxial oxy group effectcarbohydrate[Pd] catalystregioselective sulfonylationsite-switchable selectivitystereoelectronic effects

Identifiers

PMID41614160
PMCPMC12848703

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.