Evidence map›Paper›PMID 41614100›Full record

ArticleFrontiers in psychiatry2025

Neurocognitive risk markers in first-episode major depressive disorder with positive family history: a large-scale case-control study.

Zhiyong Li, Min Pan, Xulai Zhang, Anzhen Wang, Wenmei Fang, Jianjun Guan, Boyu Zhang, Xialong Cheng

Abstract read
In one paragraph

Article in Frontiers in psychiatry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Zhiyong Li *Department of Psychiatry, The Affiliated Psychological Hospital of Anhui Medical University, Hefei, China.
Min Pan *Department of Psychiatry, The Affiliated Psychological Hospital of Anhui Medical University, Hefei, China.
Xulai ZhangDepartment of Psychiatry, The Affiliated Psychological Hospital of Anhui Medical University, Hefei, China.
Anzhen WangDepartment of Psychiatry, The Affiliated Psychological Hospital of Anhui Medical University, Hefei, China.
Wenmei FangDepartment of Psychiatry, The Affiliated Psychological Hospital of Anhui Medical University, Hefei, China.
Jianjun GuanDepartment of Psychiatry, The Affiliated Psychological Hospital of Anhui Medical University, Hefei, China.
Boyu ZhangDepartment of Psychiatry, The Affiliated Psychological Hospital of Anhui Medical University, Hefei, China.
Xialong ChengDepartment of Psychiatry, The Affiliated Psychological Hospital of Anhui Medical University, Hefei, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To identify specific neurocognitive risk markers in first-episode major depressive disorder (MDD) patients with positive family history (PFH). Methods: Antipsychotic-naive adults aged 18-60 were recruited across three groups: major depressive disorder patients with positive family history (PFH-MDD, Results: The RBANS total and domain scores differed across the groups ( Conclusions: Language dysfunction and global cognitive impairment may be independent markers of first-episode MDD with PFH. Early cognitive profiling may facilitate targeted prevention in high-risk relatives.

Indexed as

family historymajor depressive disorderneurocognitionRBANSrisk marker

Identifiers

PMID41614100
PMCPMC12848912

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.