Evidence map›Paper›PMID 41614091›Full record

ArticleStatistics and computing2026

Unifying Summary Statistic Selection for Approximate Bayesian Computation.

Till Hoffmann, Jukka-Pekka Onnela

Abstract read
In one paragraph

Article in Statistics and computing, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Till HoffmannDepartment of Biostatistics, Harvard T.H. Chan School of Public Health, 655 Huntington Ave, Boston, Massachusetts 02115 USA.
Jukka-Pekka OnnelaDepartment of Biostatistics, Harvard T.H. Chan School of Public Health, 655 Huntington Ave, Boston, Massachusetts 02115 USA.

Funding

Bridging Statistical Inference and Mechanistic Network Models for HIV/AIDSR01AI138901 · NIAID · HARVARD UNIVERSITY D/B/A HARVARD SCHOOL OF PUBLIC HEALTH · PI Ravi Goyal, Jukka-Pekka Onnela · 2019 to 2026
$3.4M
NIAID NIH HHS R01 AI138901
6 · The paper itself

Abstract

Extracting low-dimensional summary statistics from large datasets is essential for efficient (likelihood-free) inference. We characterize three different classes of summaries and demonstrate their importance for correctly analyzing dimensionality reduction algorithms. We demonstrate that minimizing the expected posterior entropy (EPE) under the prior predictive distribution of the model provides a unifying principle that subsumes many existing methods; they are shown to be equivalent to, or special or limiting cases of, minimizing the EPE. We offer a unifying framework for obtaining informative summaries and propose a practical method using conditional density estimation to learn high-fidelity summaries automatically. We evaluate this approach on diverse problems, including a challenging benchmark model with a multi-modal posterior, a population genetics model, and a dynamic network model of growing trees. The results show that EPE-minimizing summaries can lead to posterior inference that is competitive with, and in some cases superior to, dedicated likelihood-based approaches, providing a powerful and general tool for practitioners.

Indexed as

Conditional Density EstimationData CompressionInformation TheoryLikelihood-Free InferenceSimulation-Based Inference

Identifiers

PMID41614091
PMCPMC12847231

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.