Evidence map›Paper›PMID 41614006›Full record

ReviewCanadian respiratory journal2026

Asthma in Patients With Confirmed Pulmonary Sarcoidosis.

Agata Anna Lewandowska, Dorota Waśniowska, Małgorzata Kołodziej, Helena Mirus-Arabik, Aleksandra Gaczkowska, Ola Duszyńska, Krzysztof Bułat, Michał Graczyk, Cezary Rybacki

Abstract readReview
In one paragraph

Review in Canadian respiratory journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Agata Anna LewandowskaClinical Department of Pulmonology, Allergology and Pulmonary Oncology, 10th Military Clinical Hospital with Polyclinic, Bydgoszcz, Poland.ORCID 0000-0002-0966-8467
Dorota WaśniowskaClinical Department of Pulmonology, Allergology and Pulmonary Oncology, 10th Military Clinical Hospital with Polyclinic, Bydgoszcz, Poland.ORCID 0009-0003-9338-4858
Małgorzata KołodziejClinical Department of Pulmonology, Allergology and Pulmonary Oncology, 10th Military Clinical Hospital with Polyclinic, Bydgoszcz, Poland.ORCID 0009-0001-4360-1039
Helena Mirus-ArabikClinical Department of Pulmonology, Allergology and Pulmonary Oncology, 10th Military Clinical Hospital with Polyclinic, Bydgoszcz, Poland.ORCID 0000-0001-9941-2619
Aleksandra GaczkowskaClinical Department of Pulmonology, Allergology and Pulmonary Oncology, 10th Military Clinical Hospital with Polyclinic, Bydgoszcz, Poland.ORCID 0009-0007-3683-599X
Ola DuszyńskaClinical Department of Pulmonology, Allergology and Pulmonary Oncology, 10th Military Clinical Hospital with Polyclinic, Bydgoszcz, Poland.
Krzysztof BułatClinical Department of Pulmonology, Allergology and Pulmonary Oncology, 10th Military Clinical Hospital with Polyclinic, Bydgoszcz, Poland.
Michał GraczykDepartment of Palliative Care, Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University, Toruń, Poland, umk.pl.ORCID 0000-0002-9121-6274
Cezary RybackiClinical Department of Pulmonology, Allergology and Pulmonary Oncology, 10th Military Clinical Hospital with Polyclinic, Bydgoszcz, Poland.ORCID 0009-0002-6840-9323

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pulmonary sarcoidosis and asthma can present identical symptoms, making clinical evaluation difficult if the two diseases overlap. Diagnostic challenges often lead to either overdiagnosis of asthma in patients with confirmed sarcoidosis or withholding appropriate asthma treatment. The true prevalence of patients with bronchial hyperresponsiveness, the hallmark of asthma, among sarcoidosis patients remains unknown, although it is suspected to be significantly higher compared to the general population. Therefore, a positive bronchial challenge test, often considered crucial for confirming asthma in symptomatic individuals with normal spirometry, should not be regarded as decisive in patients with pulmonary sarcoidosis. However, the coexistence of both diseases is possible and should always be considered. Caution is advised as patients prematurely and incorrectly diagnosed with asthma are exposed to unnecessary medical costs and lifelong treatment. Nevertheless, inhaled glucocorticosteroids and bronchodilators may be temporarily used in sarcoidosis patients because of their beneficial effect on symptom control, regardless of a concurrent asthma diagnosis. Despite the existing evidence that patients with sarcoidosis can develop asthma and atopy, the complex cellular pathways and genetic predispositions involved in the pathogenesis of both diseases remain largely unknown. To address these issues in clinical practice, the article aims to discuss the mechanisms involved in the etiopathogenesis of asthma and sarcoidosis and to analyze the available diagnostic and therapeutic methods relevant to both conditions.

Indexed as

AsthmaSarcoidosis, PulmonaryBronchial HyperreactivityBronchial Provocation TestsHumansasthmabronchial hyperresponsivenessbronchial provocation challengemethacholinesarcoidosis

Identifiers

PMID41614006
PMCPMC12848543

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.