ReviewBiophysical reviews2025
Monitoring presynaptic calcium dynamics with membrane-impermeant fluorescent indicators in motor nerve endings.
Review in Biophysical reviews, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Calcium entry through voltage-gated calcium channels as well as calcium release from intracellular calcium depots is crucial for triggering the release of neurotransmitters, synaptic plasticity and regulating the activity of various intracellular proteins. Recent evidence suggests that neuronal calcium signaling is impaired in many neurodegenerative disorders. This review presents methodological approaches that allow the estimation of the dynamics of calcium entry in motor nerve endings using fluorescent calcium indicators. The methods considered were: selecting calcium dyes depending on the experimental conditions, and loading indicators into the cells of interest. This review outlines general principles and techniques to record fast fluorescent calcium signals. Possible results that can be obtained within the framework of experiments using the described methods are also presented. Supplementary Information: The online version contains supplementary material available at 10.1007/s12551-025-01336-4.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.