ReviewBiophysical reviews2025
Biomimetic supramolecular systems: noncovalent strategy in self-assembly, functional activity and drug delivery.
Review in Biophysical reviews, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- The Synergy of Macrocycles and Heterocycles: A Review of Coordination Behavior, Sensing, and Functional Materials Based on Calixarenes.Molecules (Basel, Switzerland) · 2026Review
- Programmable phase transition enables tunable microstructures and micromechanics in thermoresponsive polysaccharide hydrogels.Communications materials · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The review focuses on biomimetic approach to the designing multifunctional nanosystems and their application in modern nanotechnology, particularly in the fields of nanomedicine, enzymology, catalysis, and drug delivery. The throughline integrating the chapters of the review is the family of amphiphilic compounds, including surfactants, macrocycles, and mixed compositions. These are very attractive building blocks due to their ability to cooperative or stoichiometric noncovalent interactions with the formation of smart supramolecular assemblies responsive to external stimulus, demonstrating tunable structural and functional behavior. Special attention is devoted to mixed micellar systems, metallosurfactants and macrocycles of different classes, including cyclodextrins, calixarenes, cucurbiturils, pillararenes. These amphiphilic assemblies are widely used as micellar nanocontainers for drug solubilization, biomimetic nanocatalysts for hydrolysis and oxidation-reduction reactions, and artificial ion channels. Amphiphilic molecules, due to their structural similarity to lipid molecules, can integrate with lipid membranes, modifying their properties. This makes amphiphiles important for developing drug delivery systems that have improved bioavailability, stability, prolonged circulation time, and the ability to overcome biological barriers, ultimately improving the effectiveness of pharmacotherapy.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.