Evidence map›Paper›PMID 41613822›Full record

ArticleTherapeutic advances in ophthalmology

Intrascleral fixation of standard capsular tension ring: a modified-simple technique for managing moderate and severe subluxated lens extraction.

Li Ning, Yingying Hong, Yinghong Ji

Registry-linked trialAbstract read
In one paragraph

Article in Therapeutic advances in ophthalmology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06627062 (Intrascleral Fixation of Standard Capsular Tension Ring: a Modified-simple Technique for Managing Moderate and Severe Subluxated Lens Extraction), which is not on this map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06627062 completednot on this map

Intrascleral Fixation of Standard Capsular Tension Ring: a Modified-simple Technique for Managing Moderate and Severe Subluxated Lens Extraction

TypeobservationalSponsorEye & ENT Hospital of Fudan UniversityRan2023 to 2024Enrolled9ConditionsLens SubluxationArmsmoderate and severe subluxated lens extraction
3 · Its place in the literature

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0 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

3 authors.

Li NingEye Institute and Department of Ophthalmology, Eye & ENT Hospital, Fudan University, Shanghai, China.
Yingying HongEye Institute and Department of Ophthalmology, Eye & ENT Hospital, Fudan University, Shanghai, China.
Yinghong JiEye Institute and Department of Ophthalmology, Eye & ENT Hospital, Fudan University, Shanghai, China.ORCID https://orcid.org/0000-0003-3340-5373

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Moderate-to-severe lens subluxation poses surgical challenges due to extensive zonular weakness and the need to maintain stable intraocular lens (IOL) positioning while preserving the capsular bag. Objectives: To evaluate the outcomes and safety of a modified technique using intrascleral suture fixation of a standard capsular tension ring (CTR) to preserve the capsular bag in moderate-to-severe lens subluxation. Design: Retrospective, single-center case series. Methods: Consecutive eyes with 120°-300° zonular dialysis underwent phacoemulsification via a 2.4 mm clear corneal incision and a 0.8 mm lateral incision. Capsular bag stabilization was achieved by intrascleral fixation of a standard CTR using a knotless Z-suture with double-strand 8-0/9-0 polypropylene, followed by in-the-bag IOL implantation. Primary outcomes were postoperative IOL centration and corrected-distance visual acuity (CDVA); secondary outcomes included refractive error and complications. Follow-up was scheduled at 1, 3, 6 months (some at 12 months) and annually thereafter. Results: Sixteen eyes of nine patients were included. Median follow-up was 328.0 days (interquartile range (IQR) 256.5, 443.0). Median logMAR CDVA improved from 0.35 (IQR 0.30, 0.57) preoperatively to 0.19 postoperatively. Mean absolute spherical equivalent decreased from 9.82 ± 1.02 D to 1.16 ± 0.25 D. IOLs were well‑centered in 13 eyes (81.3%); a slight, clinically insignificant tilt was observed in 3 eyes (18.7%). One intraoperative posterior capsule rupture did not preclude in-the-bag IOL implantation. Two eyes had transient postoperative intraocular pressure elevation managed medically. No other significant complications occurred. Conclusion: Intrascleral fixation of a standard CTR is a simple, accessible, and effective bag-preserving technique for moderate-to-severe lens subluxation, enabling stable in-the-bag IOL implantation with favorable visual and refractive outcomes. Registration: ClinicalTrials.gov: NCT06627062.

Indexed as

capsular bagcapsular tension ringintrascleral fixationsubluxated lenssurgical technique

Identifiers

PMID41613822
PMCPMC12847647

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.