ArticleCureus2025
Emerging Trimethoprim-Sulfamethoxazole Resistance Among Pathogens Isolated From Diabetic Foot Ulcers: A Case Emphasizing Early Culture-Guided Therapy.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Lower extremity ulcers are a major complication of diabetic disease, often leading to a source of infection for patients. Due to delayed wound healing, ulcers quickly develop into extensive lesions leading to infections that are polymicrobial in nature and highly likely to acquire antibiotic resistance. We present the case of a 44-year-old man with poorly controlled type 2 diabetes mellitus who developed an ulcer on the left lower extremity after an episode of mild pruritus. Failure of early patient presentation to the office resulted in the propagation of infection, including areas of depth and necrosis. The ulcer was initially treated with trimethoprim-sulfamethoxazole (SXT) until cultures revealed a polymicrobial infection of
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