ArticleCureus2025
Prevalence of Depression and Its Impact on Quality of Life in Cancer Survivors: An Observational Study From South India.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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Who cites it
1 citing paper in PubMed.
- Depression and anxiety symptoms and their association with quality of life in patients with colorectal cancer: A cross-sectional study.The South African journal of psychiatry : SAJP : the journal of the Society of Psychiatrists of South Africa · 2026Article
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Authors and funding
7 authors.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundAdvances in cancer therapy have extended survival, shifting focus toward survivorship and quality of life (QoL). Depression is a common but under-recognized issue among cancer survivors, influencing psychological adaptation and well-being.
aimTo assess the prevalence of depression and its impact on quality of life among cancer survivors beyond one year of diagnosis.
methodsA cross-sectional study was conducted among 55 cancer survivors at a tertiary care centre. Depression was assessed using the Hamilton Depression Rating Scale (HAM-D), and QoL was evaluated with the WHOQOL-BREF questionnaire (covering physical, psychological, social, and environmental domains).
resultsThe mean age of the study participants was 55.7 ± 11.5 years; 15 (27.3%) were male and 40 (72.7%) female. Depression was observed in 42 survivors (76%), of whom 22 (52.3%) had mild depression, 14 (33.3%) had moderate depression, and 6 (14.2%) had severe depression. The mean WHOQOL-BREF scores were 55.7 in the physical domain, 54.6 in the psychological domain, 52.1 in the social domain, and 77.5 in the environmental domain. Quality of life declined progressively with increasing severity of depression, with individuals experiencing severe depression reporting the lowest scores across domains.
conclusionDepression is highly prevalent among cancer survivors (76%) and strongly associated with impaired QoL, especially in environmental (Mean score:77.5) and physical domains (Mean score:55.7). Routine psychosocial screening and integrative supportive interventions are essential to optimize survivorship outcomes.
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