Evidence map›Paper›PMID 41613631›Full record

ArticleCase reports in dermatological medicine2026

Adipose-Derived Mesenchymal Stem Cell Secretome for Post-Steroid Hypopigmentation and Skin Atrophy: A Case Report.

Shannaz Nadia Yusharyahya, Valdi Ven Japranata, Endi Novianto

Abstract read
In one paragraph

Article in Case reports in dermatological medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Shannaz Nadia YusharyahyaDepartment of Dermatology and Venereology, Dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia.ORCID https://orcid.org/0000-0003-4786-3375
Valdi Ven JapranataFaculty of Medicine, University of Indonesia, Jakarta, Indonesia, ui.ac.id.ORCID https://orcid.org/0000-0001-8215-9418
Endi NoviantoDepartment of Dermatology and Venereology, Dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia.ORCID https://orcid.org/0000-0002-8688-4948

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Skin hypopigmentation and atrophy are the most commonly reported local adverse effects following corticosteroid application. While these changes are typically reversible, the recovery may be delayed or incomplete in older adults due to diminished physiological reserves and age-related reductions in melanocyte function and dermal regenerative capacity. Adipose-derived mesenchymal stem cells (ADMSCs) secretome may offer substantial benefits in reversing the alterations. In this report, we present the clinical evaluation of an elderly patient with steroid-induced cutaneous manifestations receiving ADMSCs secretome administered with intradermal injection and microneedling. Given that corticosteroid-induced atrophy and hypopigmentation may improve spontaneously, this case does not establish treatment efficacy; rather, it describes a clinical observation. The potential mechanisms by which ADMSCs secretome may facilitate improvement are also discussed.

Indexed as

adipose-derived mesenchymal stem cellscase reportcorticosteroidspostinflammatory hypopigmentationskin atrophy

Identifiers

PMID41613631
PMCPMC12848601

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.