Evidence map›Paper›PMID 41613594›Full record

ReviewFrontiers in cellular and infection microbiology2025

The potential role and value of vitamin D in the treatment of tuberculosis.

Meng Zeng, Jiyu Ran, Yun Luo, Xue Zhou, Yan Hu, Xiangyu Tian

Abstract readReview
In one paragraph

Review in Frontiers in cellular and infection microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Vitamin D3 contribution to systemic and local control ofFrontiers in molecular biosciences · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Meng ZengDepartment of Clinical Laboratory, The Affiliated Yongchuan Hospital of Chongqing Medical University, Chongqing, China.
Jiyu RanDepartment of Clinical Laboratory, The Affiliated Yongchuan Hospital of Chongqing Medical University, Chongqing, China.
Yun LuoDepartment of Clinical Laboratory, The Affiliated Yongchuan Hospital of Chongqing Medical University, Chongqing, China.
Xue Zhou *Tuberculosis Reference Laboratory, Chongqing Tuberculosis Control Institute, Chongqing, China.
Yan Hu *Tuberculosis Reference Laboratory, Chongqing Tuberculosis Control Institute, Chongqing, China.
Xiangyu TianDepartment of Clinical Laboratory, Chongqing Yongchuan District Ji'ai Hospital, Chongqing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tuberculosis remains a prevalent and serious chronic bacterial infection worldwide. Despite significant advancements in TB treatment in recent years, it continues to pose a major public health challenge. The onset and progression of TB are closely associated with individuals who are immunocompromised, as most patients also present comorbidities such as HIV, diabetes mellitus, and nutritional deficiencies. Consequently, the development of new, non-toxic immunomodulatory drugs or treatment strategies may offer viable solutions to these issues. Vitamin D not only plays a crucial role in regulating calcium and phosphate metabolism while maintaining bone health but is also a key regulator of the innate immune response against microbial infections. Furthermore, many tuberculosis patients exhibit low levels of vitamin D; thus, vitamin D may represent an important resource for enhancing immune responses against

Indexed as

Antitubercular AgentsMycobacterium tuberculosisTuberculosisVitamin DAnimalsHumansImmunity, InnateAntitubercular AgentsVitamin DinfectionMycobacterium tuberculosistreatmenttuberculosisvitamin D

Identifiers

PMID41613594
PMCPMC12847368

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.