Evidence map›Paper›PMID 41613344›Full record

ArticleAmerican journal of preventive cardiology2026

Trends in lipoprotein(a) testing and impact on clinical care: A contemporary systemwide analysis.

Mahima Mangla, Tia Bimal, Ehimare Akhabue, Xueqi Huang, Marlys Koschinsky, Georgeta Vaidean, James Donnelly, Tanesh Ayyalu, Guy Mintz, Eugenia Gianos

Abstract read
In one paragraph

Article in American journal of preventive cardiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Gaps and disparities in Lp(a) testing before universal screening: A 10-year analysis.International journal of cardiology. Cardiovascular risk and prevention · 2026
    Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Mahima ManglaNorthwell, Department of Internal Medicine, Lenox Hill Hospital, New York, NY USA.
Tia BimalNorthwell, Cardiovascular Institute, Lenox Hill Hospital, New York, NY USA.
Ehimare AkhabueNorthwell, Cardiovascular Institute, North Shore University Hospital, Manhasset, NY, USA.
Xueqi HuangNorthwell, Biostatistics Unit, Office of Academic Affairs, New Hyde Park, NY, USA.
Marlys KoschinskyRobarts Research Institute, Schulich School of Medicine & Dentistry, Western University, London, ON, Canada.
Georgeta VaideanCardiovascular Prevention Forum, Miami, FL, USA.
James DonnellyNorthwell, Center for Advanced Medicine, Clinical Laboratories, New Hyde Park, NY, USA.
Tanesh AyyaluNorthwell, Cardiovascular Institute, Lenox Hill Hospital, New York, NY USA.
Guy MintzNorthwell, Cardiovascular Institute, North Shore University Hospital, Manhasset, NY, USA.
Eugenia GianosNorthwell, Cardiovascular Institute, Lenox Hill Hospital, New York, NY USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aims: Elevated lipoprotein(a) [Lp(a)] is an independent, causal risk factor for atherosclerotic cardiovascular disease (ASCVD), yet testing remains low. As our health system has expanded its efforts to increase Lp(a) awareness, we evaluated testing rates and their impact on care. Methods: Lp(a) testing rates were collected through electronic health record queries between 1/1/2022 to 12/31/2024. Baseline demographics, ASCVD status, Lp(a) testing rates by specialty, lipid lowering therapy (LLT) prescriptions and number of cardiology referrals were collected. Results: 450,412 outpatients had ≥1 lipid panel order and 3.7 % ( Conclusion: While Lp(a) testing was low, it increased substantially over time. High risk Lp(a) levels were found irrespective of ASCVD status and were associated with more aggressive treatment. Systematic strategies to increase Lp(a) awareness and testing are warranted to mitigate cardiovascular risk.

Indexed as

AtherosclerosisCardiologyCardiovascular diseasesHeart disease risk factorsLipoprotein(a)PreventionQuality improvement

Identifiers

PMID41613344
PMCPMC12848999

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.