Evidence map›Paper›PMID 41613224›Full record

ArticleRSC advances2026

Chemical reactivity of 2-methylchromone with some nitrogen-based nucleophiles: reactions, DFT analysis, anticancer activity and molecular docking studies.

Mohamed Abdel-Megid, Najla A Alshaye, Al-Shimaa Badran, Magdy A Ibrahim

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in RSC advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Mohamed Abdel-MegidDepartment of Chemistry, College of Science, Imam Mohammad Ibn Saud Islamic University (IMSIU) Riyadh Saudi Arabia moabmohamed@imamu.edu.sa.
Najla A AlshayeDepartment of Chemistry, College of Science, Princess Nourah Bint Abdulrahman University P. O. Box 84428 Riyadh 11671 Saudi Arabia naalshaye@pnu.edu.sa.
Al-Shimaa BadranDepartment of Chemistry, Faculty of Education, Ain Shams University Roxy 11711 Cairo Egypt badran.shimaa@yahoo.com +20 022581243 +20 01011444940.ORCID https://orcid.org/0000-0003-0138-9794
Magdy A IbrahimDepartment of Chemistry, Faculty of Education, Ain Shams University Roxy 11711 Cairo Egypt badran.shimaa@yahoo.com +20 022581243 +20 01011444940.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The current study investigates the reactivity of 2-methylchromone toward nitrogen-containing heterocyclic amines, with the aim of assessing how substitution pattern and nucleophile type influence chromone ring opening and subsequent heterocycle formation. Reaction of 2-methylchromone (1) with selected heterocyclic amines afforded a series of heterocycle-linked enaminones 5, 8 and 9, which were found to preferentially adopt the

Identifiers

PMID41613224
PMCPMC12848755

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.