Evidence map›Paper›PMID 41613200›Full record

ArticleJDS communications2025

Association between postpartum systemic inflammation and serum calcium in healthy multiparous dairy cows: An exploratory observational analysis.

R Couto Serrenho, R C Neves, S J LeBlanc

Abstract read
In one paragraph

Article in JDS communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

R Couto SerrenhoDepartment of Population Medicine, University of Guelph, Guelph, ON, Canada N1G 2W1.
R C NevesDepartment of Veterinary Clinical Sciences, College of Veterinary Medicine, Purdue University, West Lafayette, IN 47907.
S J LeBlancDepartment of Population Medicine, University of Guelph, Guelph, ON, Canada N1G 2W1.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Our objective was to investigate the association between serum total Ca concentration (tCa) and indicators of systemic inflammation (SI) in postpartum dairy cows. We hypothesized that the tCa-SI association varies in the first 8 d of lactation. This exploratory analysis used data from a field trial in which cows were randomly assigned to receive oral Ca supplementation after calving (OSCa), or not. Healthy multiparous cows (total n = 101; n OSCa = 51) from 2 farms in Ontario, Canada, were included. The inflammatory markers assessed were serum concentrations of albumin (a negative acute phase protein), and the positive acute phase proteins haptoglobin and serum amyloid A (SAA). Albumin, haptoglobin, and tCa were assessed at 0 (<12 h after calving), 0.5 (12 h), 1, 2, 4, 6, and 8 d after parturition; SAA was assessed at d 0, 2, and 4. Linear regression models were fitted while accounting for time as a repeated measure for each analyte, and included tCa, tCa

Identifiers

PMID41613200
PMCPMC12848268

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.