Evidence map›Paper›PMID 41613199›Full record

ArticleJDS communications2025

Evaluating bacterial growth in raw, frozen, and heat-treated colostrum inoculated with fecal

A M McKane, T A Westhoff, S Klaessig, C Altier, K E Bell, P D Pavinski Bitar, S Mann

Abstract read
In one paragraph

Article in JDS communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

A M McKaneDepartment of Population Medicine and Diagnostic Services, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853.
T A WesthoffDepartment of Population Medicine and Diagnostic Services, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853.
S KlaessigDepartment of Population Medicine and Diagnostic Services, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853.
C AltierDepartment of Population Medicine and Diagnostic Services, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853.
K E BellDepartment of Population Medicine and Diagnostic Services, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853.
P D Pavinski BitarDepartment of Population Medicine and Diagnostic Services, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853.
S MannDepartment of Population Medicine and Diagnostic Services, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853.

Funding

Cornell University Combined DVM-PhD Medical Scientist Training Program (MSTP)T32GM150453 · NIGMS · CORNELL UNIVERSITY · PI Renata Ivanek Miojevic · 2023 to 2026
$941k
NIGMS NIH HHS T32 GM150453
6 · The paper itself

Abstract

Providing newborn calves with sufficient high-quality colostrum is a critical calf-management strategy to support health, survival, and future productivity. Unfortunately, colostrum may also serve as a fomite for disease when contaminated with bacteria at harvest, during storage, or during reheating before feeding. Thermal processing, including heat treatment (HT; 60°C for 60 min) and freezing (FR; -20°C), are common strategies to manage bacterial contamination. Although both strategies maintain IgG concentrations, they destroy colostral immune cells, and HT is known to decrease the concentration and activity of certain bioactive factors such as complement and IgA. We hypothesized that HT and FR would influence the inherent antibacterial properties of bovine colostrum compared with unprocessed, refrigerated colostrum (RW). Our objective was thus to compare growth of

Identifiers

PMID41613199
PMCPMC12848265

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.