Evidence map›Paper›PMID 41613181›Full record

ArticleFrontiers in neurology2025

Effect of ultrasound-guided scalp nerve block on hemodynamics and postoperative agitation in hypertensive cerebral hemorrhage craniotomy patients: a prospective randomized controlled study.

Bing Li, Zhifang Cao, Junlong Huang, Ying Chen, Zhihua Li, Weiming Wu, Chuntian Li, Ting Qiu, Juncheng Chen

Registry-linked trialAbstract read
In one paragraph

Article in Frontiers in neurology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07545655 (Investigation of the Effects of Preoperative Ultrasound-Guided Scalp Block on Perioperative Opioid Consumption, Hemodynamic Stability, and Inflammatory Response in Patients Undergoing Craniotomy With a Skull Pin Head Holder), which is not on this map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07545655 not yet recruitingnot on this mapstarted 2026, after this paper: background citation

Investigation of the Effects of Preoperative Ultrasound-Guided Scalp Block on Perioperative Opioid Consumption, Hemodynamic Stability, and Inflammatory Response in Patients Undergoing Craniotomy With a Skull Pin Head Holder

Typeobservational_patient_registrySponsorFatih Sultan Mehmet Training and Research HospitalRan2026 to 2027Enrolled60ConditionsCraniotomy Surgery
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Bing LiDepartment of Anesthesiology, Longyan First Affiliated Hospital of Fujian Medical University, Longyan, China.
Zhifang CaoDepartment of Anesthesiology, Longyan First Affiliated Hospital of Fujian Medical University, Longyan, China.
Junlong HuangDepartment of Neurosurgery, Longyan First Affiliated Hospital of Fujian Medical University, Longyan, China.
Ying ChenDepartment of Anesthesiology, Longyan First Affiliated Hospital of Fujian Medical University, Longyan, China.
Zhihua LiDepartment of Anesthesiology, Longyan First Affiliated Hospital of Fujian Medical University, Longyan, China.
Weiming WuDepartment of Anesthesiology, Longyan First Affiliated Hospital of Fujian Medical University, Longyan, China.
Chuntian LiDepartment of Anesthesiology, Longyan First Affiliated Hospital of Fujian Medical University, Longyan, China.
Ting QiuDepartment of Anesthesiology, Longyan First Affiliated Hospital of Fujian Medical University, Longyan, China.
Juncheng ChenDepartment of Anesthesiology, Longyan First Affiliated Hospital of Fujian Medical University, Longyan, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: This study aims to investigate the impact of dexmedetomidine combined with ropivacaine scalp nerve block (SNB) on analgesic effects in patients undergoing craniotomy for hypertensive intracerebral hemorrhage (HICH). Methods: A prospective randomized controlled trial was conducted on 120 HICH patients who underwent craniotomy at Longyan First Affiliated Hospital of Fujian Medical University from May 2022 to April 2024. Patients were randomly divided into three groups: control group (A, no SNB), ropivacaine SNB group (B, 0.5% ropivacaine), and dexmedetomidine-ropivacaine SNB group (C, 0.5% ropivacaine + 0.5 μg/kg dexmedetomidine), with 40 patients in each group. Primary outcomes included intraoperative hemodynamic parameters [mean arterial pressure (MAP), heart rate (HR)], intraoperative anesthetic consumption, postoperative Visual Analogue Scale (VAS) scores, rescue analgesia requirements, and incidence of adverse reactions within 48 h postoperatively. Results: General characteristics were comparable among the three groups ( Conclusion: Dexmedetomidine combined with ropivacaine for SNB improves postoperative analgesia, stabilizes intraoperative hemodynamics, reduces anesthetic usage and rescue analgesia needs, and lowers the incidence of adverse reactions in HICH craniotomy patients, making it a safe and effective analgesic strategy. Clinical trial registration: chictr.org.cn, identifier ChiCTR2500106043.

Indexed as

craniotomydexmedetomidinehypertensive intracerebral hemorrhagepostoperative analgesiaropivacainescalp nerve block

Identifiers

PMID41613181
PMCPMC12847037

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Registered trials

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