Evidence map›Paper›PMID 41613178›Full record

SynthesisFrontiers in neurology2025

Relationship between early venous filling after thrombectomy and intracranial hemorrhage and prognosis in patients with acute ischemic stroke: a systematic review and meta-analysis.

Xiaoyu Wu, Chao Li, Mingchao Shi, Kangjia Song, Mingchen Zhang, Siyuan Wang, Shouchun Wang

Abstract readSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Frontiers in neurology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Xiaoyu WuStroke Center, Department of Neurology, The First Hospital of Jilin University, Changchun, China.
Chao LiStroke Center, Department of Neurology, The First Hospital of Jilin University, Changchun, China.
Mingchao ShiStroke Center, Department of Neurology, The First Hospital of Jilin University, Changchun, China.
Kangjia SongStroke Center, Department of Neurology, The First Hospital of Jilin University, Changchun, China.
Mingchen ZhangStroke Center, Department of Neurology, The First Hospital of Jilin University, Changchun, China.
Siyuan WangStroke Center, Department of Neurology, The First Hospital of Jilin University, Changchun, China.
Shouchun WangStroke Center, Department of Neurology, The First Hospital of Jilin University, Changchun, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: This study aims to assess the relationship between early venous filling (EVF) observed during mechanical thrombectomy and 90-day functional independence (mRS ≤ 2) as well as postoperative intracranial hemorrhage (ICH) and symptomatic intracranial hemorrhage (SICH), in patients with acute ischemic stroke. Methods: We conducted a systematic search of the PubMed, EMBASE, Web of Science, and Cochrane Library databases up to September 26, 2024, following the PRISMA 2020 guidelines. The primary clinical outcomes were defined as 90-day functional independence (mRS ≤ 2) and SICH, while the secondary clinical outcome was ICH. Odds ratios (OR) and 95% confidence intervals (CI) were estimated using a random-effects model. Results: A total of six studies that met the inclusion criteria were analyzed. Meta-analysis demonstrated that patients with EVF had a significantly reduced likelihood of achieving 90-day functional independence compared to patients without EVF (OR 0.42, 95% CI 0.18-0.99, Conclusion: EVF may serve as an intraoperative angiographic marker associated with a higher incidence of postoperative ICH, SICH, and poorer 90-day functional independence. Systematic review registration: https://www.crd.york.ac.uk/PROSPERO/, identifier CRD42024595410.

Indexed as

acute ischemic strokeearly venous fillingendovascular treatmentprognosicthrombectomy

Identifiers

PMID41613178
PMCPMC12848917

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.