Evidence map›Paper›PMID 41613132›Full record

ReviewFrontiers in immunology2025

The pediatric nasal microbiome and its role in chronic ENT disorders: a narrative review.

Adriana Elena Sîrbu, Gratiela Gradisteanu Pircalabioru, Diana Maria Deaconu, Octavian Andronic, Dan Cristian Gheorghe

Abstract readReview
In one paragraph

Review in Frontiers in immunology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Adriana Elena SîrbuFaculty of Medicine, "Carol Davila" University of Medicine and Pharmacy, Bucharest, Romania.
Gratiela Gradisteanu PircalabioruDepartment of Botany and Microbiology, Faculty of Biology, University of Bucharest, Bucharest, Romania.
Diana Maria DeaconuDepartment of Botany and Microbiology, Faculty of Biology, University of Bucharest, Bucharest, Romania.
Octavian AndronicInnovation and eHealth Center, Carol Davila University of Medicine and Pharmacy Bucharest, Bucharest, Romania.
Dan Cristian GheorgheFaculty of Medicine, "Carol Davila" University of Medicine and Pharmacy, Bucharest, Romania.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The human microbiome is increasingly recognized as a key factor in immune development and disease susceptibility, especially in early life. Nasal microbiome has emerged as a critical element in upper airway health, yet its role in pediatric otorhinolaryngological conditions remains underexplored. This narrative review synthesizes current evidence on the microbial nasopharyngeal patterns in healthy children compared with children suffering from chronic ENT conditions such as otitis media, allergic rhinitis, chronic rhinosinusitis, adenoid and tonsillar hypertrophy associated with obstructive sleep apnea. A structured search of Web of Science, PubMed, Google Scholar and CrossRef databases was conducted for peer-reviewed articles published in the past ten years. Nasal microbiota of healthy children was proved to be dominated by commensal protective taxa such as

Indexed as

MicrobiotaOtorhinolaryngologic DiseasesChildChronic DiseaseHumansOtitis MediaRhinosinusitisadenoid and tonsillar hypertrophyallergic rhinitisdysbiosisnasal microbiomeotitis mediapediatric

Identifiers

PMID41613132
PMCPMC12847349

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.