Evidence map›Paper›PMID 41613066›Full record

ArticleFrontiers in public health2025

Comparative effects of cigarette smoking, e-cigarette use, and dual use on pulmonary function, exercise capacity, and quality of life in young adults: a cross-sectional study.

Gokul G Krishna, Ann M Jose, Weaam A Rahali, Wejdan W Alyamani, Manahel A Mohammed, Basmah S Alghamdi, Mazen M Homoud, Mohammed Almeshari, Khalid S Alwadeai, Saleh R Alkhathami and 2 more

Abstract readComparative Study
In one paragraph

Article in Frontiers in public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Gokul G KrishnaDepartment of Respiratory Therapy, Batterjee Medical College, Jeddah, Saudi Arabia.
Ann M JoseDepartment of Respiratory Therapy, Batterjee Medical College, Jeddah, Saudi Arabia.
Weaam A RahaliDepartment of Respiratory Therapy, Batterjee Medical College, Jeddah, Saudi Arabia.
Wejdan W AlyamaniDepartment of Respiratory Therapy, Batterjee Medical College, Jeddah, Saudi Arabia.
Manahel A MohammedDepartment of Respiratory Therapy, Batterjee Medical College, Jeddah, Saudi Arabia.
Basmah S AlghamdiDepartment of Respiratory Therapy, Batterjee Medical College, Jeddah, Saudi Arabia.
Mazen M HomoudDepartment of Respiratory Therapy, Faculty of Medical Rehabilitation Sciences, King Abdulaziz University, Jeddah, Saudi Arabia.
Mohammed AlmeshariDepartment of Rehabilitation Health Sciences, College of Applied Medical Sciences, King Saud University, Riyadh, Saudi Arabia.
Khalid S AlwadeaiDepartment of Rehabilitation Health Sciences, College of Applied Medical Sciences, King Saud University, Riyadh, Saudi Arabia.
Saleh R AlkhathamiDepartment of Medical Laboratory, King Fahad Armed Hospital, Jeddah, Saudi Arabia.
Jithin K SreedharanDepartment of Respiratory Therapy, College of Rehabilitation Sciences, University of Manitoba, Winnipeg, MB, Canada.
Ayedh D AlahmariDepartment of Rehabilitation Health Sciences, College of Applied Medical Sciences, King Saud University, Riyadh, Saudi Arabia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Tobacco smoking constitutes a primary cause of preventable cardiovascular and pulmonary diseases on a global scale. While smoking rates fall, e-cigarette use rises, especially in youth. Objective: Assess effects of smoking, vaping, and dual use on lung function, exercise capacity and quality of life. Methods: Participants were classified into five groups: Control, Cigarette use only, E-cigarettes use only, Ex-cigarette smoker current vaper, and Dual users (use of both e-cigarettes and combustible cigarettes). Participants performed spirometry, six minute walk test (6MWT) and completed health related quality of life (HRQoL) questionnaire. Results: A total of 222 participants, 86.9% were male, with median age 26 years. Age and body mass index (BMI) showed no significant differences across groups. Cigarette-only and dual users reported 20 cigarettes/day with 5-7 years smoking duration, while e-cigarette use duration was 4-5 years among exclusive vapers, ex-smoker vapers, and dual users. Spirometry revealed impairments: Forced expiratory volume in the first second (FEV Conclusion: Young adults using cigarettes and e-cigarettes showed impaired lung function and quality of life compared to never-users. Daily dual users showed the greatest declines, while former smokers using e-cigarettes showed intermediate outcomes. Exclusive e-cigarette users exhibited least impairment.

Indexed as

Cigarette SmokingElectronic Nicotine Delivery SystemsExercise ToleranceLungQuality of LifeVapingAdultCross-Sectional StudiesFemaleHumansMaleRespiratory Function TestsSpirometryYoung Adultcigarette smokingdual useelectronic cigarettesexercise testforced expiratory volumepulmonary function testsquality of lifesix-minute walk test

Identifiers

PMID41613066
PMCPMC12847274

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.