Evidence map›Paper›PMID 41612990›Full record

ArticleAnnals of gastroenterology

Predictors of a need for cholangioscopy-guided electrohydraulic lithotripsy in the management of difficult common bile duct stones.

Dionysios Kogias, Nikolaos Kafalis, Vaia Karapepera, Vasileios Papadopoulos, Georgios Kouklakis

Abstract read
In one paragraph

Article in Annals of gastroenterology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Authors' reply.Annals of gastroenterology
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Dionysios KogiasFirst Department of Internal Medicine, Democritus University of Thrace, University Hospital of Alexandroupolis, Greece (Dionysios Kogias, Nikolaos Kafalis, Georgios Kouklakis).
Nikolaos KafalisFirst Department of Internal Medicine, Democritus University of Thrace, University Hospital of Alexandroupolis, Greece (Dionysios Kogias, Nikolaos Kafalis, Georgios Kouklakis).
Vaia KarapeperaOtolaryngology - Head and Neck, Chatzikosta Hospital of Ioannina, Greece (Vaia Karapepera).
Vasileios PapadopoulosLaboratory of Anatomy, Department of Medicine, Democritus University of Thrace, Greece (Vasileios Papadopoulos).
Georgios KouklakisFirst Department of Internal Medicine, Democritus University of Thrace, University Hospital of Alexandroupolis, Greece (Dionysios Kogias, Nikolaos Kafalis, Georgios Kouklakis).

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: While standard endoscopic methods effectively clear most common bile duct stones, complex cases require specialized management. This study compared the effectiveness of cholangioscopy-guided electrohydraulic lithotripsy (EHL) against conventional techniques for treating difficult common bile duct stones (DBS). Methods: This retrospective study included 436 patients who underwent endoscopic retrograde cholangiopancreatography between April 2020 and April 2024. Demographic, laboratory and procedural data were recorded. Categorical regression identified predictors for EHL, and classification tree analysis was used to develop a prioritization algorithm. Results: Among patients with DBS (305/436, 70%), conventional methods succeeded in 28.9% (88/305). Endoscopic papillary large balloon dilation followed failed first-line techniques in 115 cases, with a 21.7% success rate. EHL was used in 192 patients, achieving a 98.4% success rate. Multivariate analysis showed that DBS (P<0.001), absence of wedged stones in the ampulla of Vater (P<0.001), and small papillae (P=0.002) were strong independent predictors for EHL use, with DBS being the most significant. Conclusions: DBS, absence of wedged stones in Vater and small papillae are key predictors of the need for cholangioscopy-guided EHL. Given its high success rate and comparable safety profile, EHL should be considered an early-line treatment in selected cases.

Indexed as

choledocholithiasiscommon bile duct stoneElectrohydraulicendoscopic retrograde cholangiopancreatographylithotripsy

Identifiers

PMID41612990
PMCPMC12850689

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.