Evidence map›Paper›PMID 41612984›Full record

ArticleAnnals of gastroenterology

A prospective international multisite randomized controlled trial of water exchange with and without distal cap(s) in adenoma detection.

Felix W Leung, Sergio Cadoni, Long Chen, Yu Chen, Chi-Liang Cheng, Ramsey Cheung, Vivek Dixit, David Elashoff, Shai Friedland, Paolo Gallittu and 21 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Annals of gastroenterology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Authors' reply.Annals of gastroenterology
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

31 authors.

Felix W LeungGastroenterology, Medicine, Sepulveda Ambulatory Care Center, Veterans Affairs Greater Los Angeles Healthcare System, North Hills, CA, USA (Felix W. Leung, Vivek Dixit, Nora Jamgotchian, Hui Jia).
Sergio CadoniPresidio Ospedaliero CTO, Iglesias, Italy (Sergio Cadoni, Paolo Gallittu, Donatella Mura).
Long ChenFourth Military Medical University, Xian, China (Long Chen, Hui Jia, Yanglin Pan, Linhui Zhang).
Yu ChenVeterans Affairs Palo Alto Health Care System, Palo Alto, CA, USA (Yu Chen, Ramsey Cheung, Shai Friedland, Jennifer Yi-Jiun Pan, Susan Y. Quan, Robert J. Wong).
Chi-Liang ChengEvergreen General Hospital, Taoyuan, Taiwan (Chi-Liang Cheng, Yen-Lin Kuo, Bai-Ping Lee, Yi-Ning Tsui).
Ramsey CheungVeterans Affairs Palo Alto Health Care System, Palo Alto, CA, USA (Yu Chen, Ramsey Cheung, Shai Friedland, Jennifer Yi-Jiun Pan, Susan Y. Quan, Robert J. Wong).
Vivek DixitGastroenterology, Medicine, Sepulveda Ambulatory Care Center, Veterans Affairs Greater Los Angeles Healthcare System, North Hills, CA, USA (Felix W. Leung, Vivek Dixit, Nora Jamgotchian, Hui Jia).
David ElashoffUniversity of California Los Angeles David Geffen School of Medicine, Los Angeles, CA, USA (Felix W. Leung, Vivek Dixit, Noam Jacob, Angshuman Saha, Holly Wilhalme).
Shai FriedlandVeterans Affairs Palo Alto Health Care System, Palo Alto, CA, USA (Yu Chen, Ramsey Cheung, Shai Friedland, Jennifer Yi-Jiun Pan, Susan Y. Quan, Robert J. Wong).
Paolo GallittuPresidio Ospedaliero CTO, Iglesias, Italy (Sergio Cadoni, Paolo Gallittu, Donatella Mura).
Yu-Hsi HsiehDalin Tzu Chi Hospital, Chiayi, Taiwan (Yu-Hsi Hsieh, Chia Hsin Cheng, Chih-Wei Tseng).
Chia Hsin ChengDalin Tzu Chi Hospital, Chiayi, Taiwan (Yu-Hsi Hsieh, Chia Hsin Cheng, Chih-Wei Tseng).
Noam JacobGastroenterology, Medicine, West Los Angeles Veterans Affairs Medical Center, Veterans Affairs Greater Los Angeles Healthcare System, West Los Angeles, CA, USA (Felix W. Leung, Vivek Dixit, Noam Jacob, James Sul).
Nora JamgotchianGastroenterology, Medicine, Sepulveda Ambulatory Care Center, Veterans Affairs Greater Los Angeles Healthcare System, North Hills, CA, USA (Felix W. Leung, Vivek Dixit, Nora Jamgotchian, Hui Jia).
Hui JiaGastroenterology, Medicine, Sepulveda Ambulatory Care Center, Veterans Affairs Greater Los Angeles Healthcare System, North Hills, CA, USA (Felix W. Leung, Vivek Dixit, Nora Jamgotchian, Hui Jia).
Yen-Lin KuoEvergreen General Hospital, Taoyuan, Taiwan (Chi-Liang Cheng, Yen-Lin Kuo, Bai-Ping Lee, Yi-Ning Tsui).
Bai-Ping LeeEvergreen General Hospital, Taoyuan, Taiwan (Chi-Liang Cheng, Yen-Lin Kuo, Bai-Ping Lee, Yi-Ning Tsui).
Joseph W LeungSacramento Veterans Affairs Medical Center, Mather, CA, USA (Joseph W. Leung, Aliya Shaikh, Andrew W. Yen).
Donatella MuraPresidio Ospedaliero CTO, Iglesias, Italy (Sergio Cadoni, Paolo Gallittu, Donatella Mura).
Jennifer Yi-Jiun PanVeterans Affairs Palo Alto Health Care System, Palo Alto, CA, USA (Yu Chen, Ramsey Cheung, Shai Friedland, Jennifer Yi-Jiun Pan, Susan Y. Quan, Robert J. Wong).
Yanglin PanFourth Military Medical University, Xian, China (Long Chen, Hui Jia, Yanglin Pan, Linhui Zhang).
Susan Y QuanVeterans Affairs Palo Alto Health Care System, Palo Alto, CA, USA (Yu Chen, Ramsey Cheung, Shai Friedland, Jennifer Yi-Jiun Pan, Susan Y. Quan, Robert J. Wong).
Angshuman SahaUniversity of California Los Angeles David Geffen School of Medicine, Los Angeles, CA, USA (Felix W. Leung, Vivek Dixit, Noam Jacob, Angshuman Saha, Holly Wilhalme).
Aliya ShaikhSacramento Veterans Affairs Medical Center, Mather, CA, USA (Joseph W. Leung, Aliya Shaikh, Andrew W. Yen).
James SulGastroenterology, Medicine, West Los Angeles Veterans Affairs Medical Center, Veterans Affairs Greater Los Angeles Healthcare System, West Los Angeles, CA, USA (Felix W. Leung, Vivek Dixit, Noam Jacob, James Sul).
Chih-Wei TsengDalin Tzu Chi Hospital, Chiayi, Taiwan (Yu-Hsi Hsieh, Chia Hsin Cheng, Chih-Wei Tseng).
Yi-Ning TsuiEvergreen General Hospital, Taoyuan, Taiwan (Chi-Liang Cheng, Yen-Lin Kuo, Bai-Ping Lee, Yi-Ning Tsui).
Holly WilhalmeUniversity of California Los Angeles David Geffen School of Medicine, Los Angeles, CA, USA (Felix W. Leung, Vivek Dixit, Noam Jacob, Angshuman Saha, Holly Wilhalme).
Robert J WongVeterans Affairs Palo Alto Health Care System, Palo Alto, CA, USA (Yu Chen, Ramsey Cheung, Shai Friedland, Jennifer Yi-Jiun Pan, Susan Y. Quan, Robert J. Wong).
Andrew W YenSacramento Veterans Affairs Medical Center, Mather, CA, USA (Joseph W. Leung, Aliya Shaikh, Andrew W. Yen).
Linhui ZhangFourth Military Medical University, Xian, China (Long Chen, Hui Jia, Yanglin Pan, Linhui Zhang).

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Interval cancers are linked to a low adenoma detection rate (ADR), prompting calls for benchmark-guided ADR performance improvement. Although water exchange and a straight cap (CAP) have been reported to independently improve ADR, the effects of Daisycuff Methods: Subjects were randomized to No cap, or CAP, Daisycuff Results: Demographic and historic data revealed adequate randomization. Despite variations in site-specific pretrial ADR, the aggregated data showed that the ADR of No cap (45.6%) exceeded the latest benchmark (35%). Each added cap increased the ADR, and the difference using Daisycuff Conclusions: The significantly higher right-colon ADRs with CAP and Daisycuff

Indexed as

adenoma detection ratedistal capWater exchange colonoscopy

Identifiers

PMID41612984
PMCPMC12850690

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.