Evidence map›Paper›PMID 41612597›Full record

ArticleAutophagy2026

Marie-Charlotte Trojani, Marie Nollet, Olivier Camuzard, Sabine Santucci-Darmanin, Véronique Breuil, Fanny Burel-Vandenbos, Laurie Fradet, Morgane Le Gall, Virginie Salnot, Dominique Heymann and 2 more

Abstract read
In one paragraph

Article in Autophagy, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Marie-Charlotte TrojaniFaculté de Médecine Nice, UMR4320 PHEN-X CEA/DRF/Institut Joliot, Université Côte d'Azur, Nice, France.
Marie NolletFaculté de Médecine Nice, UMR4320 PHEN-X CEA/DRF/Institut Joliot, Université Côte d'Azur, Nice, France.
Olivier CamuzardFaculté de Médecine Nice, UMR4320 PHEN-X CEA/DRF/Institut Joliot, Université Côte d'Azur, Nice, France.
Sabine Santucci-DarmaninFaculté de Médecine Nice, UMR4320 PHEN-X CEA/DRF/Institut Joliot, Université Côte d'Azur, Nice, France.
Véronique BreuilFaculté de Médecine Nice, UMR4320 PHEN-X CEA/DRF/Institut Joliot, Université Côte d'Azur, Nice, France.
Fanny Burel-VandenbosLaboratoire Central d'Anatomie Pathologique, Hôpital Pasteur, CHU, Nice, France.
Laurie FradetInstitut de Cancérologie de l'Ouest,CNRS, UMR6286, US2B, Nantes Université, Nantes, France.
Morgane Le GallProteom'IC Facility, Institut Cochin, CNRS, INSERM, Université, Paris Cité, Paris, France.
Virginie SalnotProteom'IC Facility, Institut Cochin, CNRS, INSERM, Université, Paris Cité, Paris, France.
Dominique HeymannInstitut de Cancérologie de l'Ouest,CNRS, UMR6286, US2B, Nantes Université, Nantes, France.
Georges F CarleFaculté de Médecine Nice, UMR4320 PHEN-X CEA/DRF/Institut Joliot, Université Côte d'Azur, Nice, France.
Valérie Pierrefite-CarleFaculté de Médecine Nice, UMR4320 PHEN-X CEA/DRF/Institut Joliot, Université Côte d'Azur, Nice, France.ORCID 0000-0003-3399-2934

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bone is an attractive site for cancer colonization, both for primary tumors such as osteosarcoma and for metastases of various malignancies. Preventing bone metastasis, which is associated with a poor prognosis, is a major challenge and identifying the factors involved in skeletal tumoral development is crucial to improve survival. In the present work, we showed that inactivation of the macroautophagy/autophagy-essential gene

Indexed as

AutophagyAutophagy-Related Protein 5Bone and BonesBone NeoplasmsCarcinogenesisTumor MicroenvironmentAnimalsExocytosisHumansLysosomesMiceOsteoblastsOsteosarcomaAtg5 protein, mouseAutophagy-Related Protein 5Autophagybone metastasisbone microenvironmentbreast cancerosteoblastosteosarcoma

Identifiers

PMID41612597
PMCPMC13232990

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.