Evidence map›Paper›PMID 41612525›Full record

Observational studyEmerging infectious diseases2026

Pulmonary Histoplasmosis, Taiwan, 1997-2024.

Ting-Wei Kao, Shang-Chen Yang, Hsiang-Wei Hu, Yu-Tsung Huang, Chin-Chung Shu, Wang-Huei Sheng

Abstract readObservational Study
In one paragraph

Observational study in Emerging infectious diseases, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Pulmonary Histoplasmosis, Taiwan, 1997-2024.Emerging infectious diseases · 2026
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ting-Wei Kao
Shang-Chen Yang
Hsiang-Wei Hu
Yu-Tsung Huang
Chin-Chung Shu
Wang-Huei Sheng

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pulmonary histoplasmosis has traditionally been considered geographically restricted to disease-endemic regions. Taiwan, historically nonendemic, has recently witnessed rising infections. We conducted a retrospective study by reviewing adult patients in Taiwan who had pathologically confirmed pulmonary histoplasmosis during June 1997-December 2024. We analyzed 14 cases with lung involvement. Eight case-patients were male and 6 female; mean age was 56.6 years. Of note, 11 case-patients (78.6%) had no history of travel to histoplasmosis-endemic regions; 10 (71.4%) were immunocompetent. Left upper lobe involvement was most common (n = 4 [28.6%]), with nodular lesions predominating (n = 12 [85.7%]). Most (11 [78.6%]) patients received antifungal therapy, mostly with voriconazole. Outcomes were favorable; 1 (7.1%) patient died. Two additional case-patients without lung involvement exhibited similar demographics and clinical outcomes. Case identification rate has increased since 2015. This 27-year study documents the emergence of pulmonary histoplasmosis in Taiwan, emphasizing the need for heightened clinical suspicion in nonendemic regions.

Indexed as

HistoplasmosisLung Diseases, FungalAdultAgedAntifungal AgentsFemaleHistoplasmaHistory, 21st CenturyHumansImmunocompetenceMaleMiddle AgedRetrospective StudiesTaiwanAntifungal Agentsdimorphic fungifungiHistoplasma capsulatumhistoplasmosisnon-endemic regionspulmonary mycosisTaiwan

Identifiers

PMID41612525
PMCPMC12870032

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.