Evidence map›Paper›PMID 41612509›Full record

ArticleEuropean journal of medical research2026

Vesicovaginal fistula repair: comparative analysis of perioperative outcomes and predictors of success in open, laparoscopic, and robotic approaches.

Zeyuan Wang, Gaurab Pokhrel, Shuanbao Yu, Haoke Zheng, Jin Tao, Yafeng Fan, Yunlong Liu, Jinjin Feng, Biao Dong, Tengfei Li and 2 more

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Article in European journal of medical research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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12 authors.

Zeyuan Wang *Department of Urology, The First Affiliated Hospital of Zhengzhou University, No. 1 Jianshe East Road, Zhengzhou, 450052, China.
Gaurab Pokhrel *Department of Urology, The First Affiliated Hospital of Zhengzhou University, No. 1 Jianshe East Road, Zhengzhou, 450052, China.
Shuanbao Yu *Department of Urology, The First Affiliated Hospital of Zhengzhou University, No. 1 Jianshe East Road, Zhengzhou, 450052, China.
Haoke ZhengDepartment of Urology, The First Affiliated Hospital of Zhengzhou University, No. 1 Jianshe East Road, Zhengzhou, 450052, China.
Jin TaoDepartment of Urology, The First Affiliated Hospital of Zhengzhou University, No. 1 Jianshe East Road, Zhengzhou, 450052, China.
Yafeng FanDepartment of Urology, The First Affiliated Hospital of Zhengzhou University, No. 1 Jianshe East Road, Zhengzhou, 450052, China.
Yunlong LiuDepartment of Urology, The First Affiliated Hospital of Zhengzhou University, No. 1 Jianshe East Road, Zhengzhou, 450052, China.
Jinjin FengDepartment of Urology, The First Affiliated Hospital of Zhengzhou University, No. 1 Jianshe East Road, Zhengzhou, 450052, China.
Biao DongDepartment of Urology, The First Affiliated Hospital of Zhengzhou University, No. 1 Jianshe East Road, Zhengzhou, 450052, China.
Tengfei LiDepartment of Urology, Kaifeng Central Hospital, Kaifeng, China.
Xuanyi RenDepartment of Urology, Kaifeng Central Hospital, Kaifeng, China.
Xuepei ZhangDepartment of Urology, The First Affiliated Hospital of Zhengzhou University, No. 1 Jianshe East Road, Zhengzhou, 450052, China. zhangxuepei@263.net.

Funding

Henan Provincial Science and Technology Research Project,China 242102311074
6 · The paper itself

Abstract

backgroundTo compare perioperative outcomes and evaluate predictors of successful repair in vesicovaginal fistula (VVF) cases among open, laparoscopic, and robotic-assisted approaches.

methodsThis retrospective cohort study included 78 patients who underwent transabdominal VVF repair between December 2015 and July 2024 at a tertiary referral center. Patients were categorized based on surgical approach: open (n = 31), laparoscopic (n = 31), or robotic-assisted (n = 16). Data collected included demographics, fistula etiology and location, prior radiation exposure, operative time, blood loss, use of interposition flaps, and 3-month postoperative closure status.

resultsMinimally invasive techniques (laparoscopic and robotic) demonstrated reduced operative time (P = 0.014) and blood loss (P < 0.001) compared to open surgery. Time to repair (P = 0.001) and previous repair attempts (P = 0.007) varied significantly across approaches. Post-hysterectomy fistulas had the highest success rate (95%), while radiation-induced (P = 0.031) and trigonal fistulas (failure rate 32% vs. 6% in non-trigonal; P = 0.004) were associated with poorer outcomes. Use of interposition flaps was more frequent in open cases but did not independently predict success. The surgical approach was not an independent predictor of closure rates; however, minimally invasive techniques were associated with better perioperative outcomes.

conclusionsThis study highlights the importance of selecting the surgical approach based on fistula characteristics and clinical context. Minimally invasive techniques provided perioperative advantages, whereas open surgery remains essential for complex cases. Careful preoperative planning and well-informed clinical decision-making are crucial to optimize management. Further prospective, multicenter studies are warranted to confirm these findings and guide standardized best practices.

Identifiers

PMID41612509
PMCPMC12924227

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