Evidence map›Paper›PMID 41612172›Full record

ArticleBMC genomics2026

Genome-wide identification and expression profiling of the NHX gene family in oat (Avena sativa L.).

Yuqi Li, Meifeng Liu, Wenjie Zhao, Feng Yuan, Zhenyu Jia, Yi Wang, Wendong Zheng, Chengchen Pan, Chunxiang Fu

Abstract read
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Article in BMC genomics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1citing papers in PubMed
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1 · What the graph read from it

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3 · Its place in the literature

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1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Yuqi LiSynthetic Biology Technology Innovation Center of Shandong Province, Qingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences, Qingdao, China.
Meifeng LiuSynthetic Biology Technology Innovation Center of Shandong Province, Qingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences, Qingdao, China.
Wenjie ZhaoSynthetic Biology Technology Innovation Center of Shandong Province, Qingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences, Qingdao, China.
Feng YuanInner Mongolia Mengcao Seed Industry Science & Technology Research Institute Co., Ltd., Hohhot, China.
Zhenyu JiaInner Mongolia Mengcao Seed Industry Science & Technology Research Institute Co., Ltd., Hohhot, China.
Yi WangQingdao Haier Biological Medical Technology Co., Ltd., Qingdao, China.
Wendong ZhengQingdao Haier Biological Medical Technology Co., Ltd., Qingdao, China.
Chengchen PanInner Mongolia Mengcao Seed Industry Science & Technology Research Institute Co., Ltd., Hohhot, China. panchengchen@lzb.ac.cn.
Chunxiang FuSynthetic Biology Technology Innovation Center of Shandong Province, Qingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences, Qingdao, China. fucx@qibebt.ac.cn.

Funding

Government-Industry-Academia-Research-Promotion-Application-Finance of Hohhot Innovation Consortium Project 2022RC-LHT-2National Key Research and Development Program of China 2023YFD1902500Qingdao New Energy Shandong Laboratory of Key Projects Programs QNESLKPP202302Taishan Scholar Program of Shandong, the Research on Key Technologies for Multi-Dimensional Microbial Culture Support & Product Industrialization 24-1-4-xxgg-11-nsh
6 · The paper itself

Abstract

backgroundSalt stress imposes osmotic imbalance and ion toxicity, severely impairing crop growth and development. Na⁺/H⁺ antiporters (NHXs) play a central role in salt tolerance by mediating sodium transport across cellular membranes.

resultsWe conducted a genome-wide characterization of the NHX gene family in four hexaploid oat cultivars, identifying 126 NHX genes. These were grouped into 33 orthologous gene groups (OGGs), comprising 10 core and 23 dispensable OGGs. The naked oat cultivar ‘Sanfensan (SFS)’ contained the largest number of both total and core NHX genes. Phylogenetic analysis classified AsNHX genes into three classes: vacuolar (Vac-class), endosomal (Endo-class), and plasma membrane (PM-class). Ka/Ks analysis indicated strong purifying selection across most members. Cis-regulatory element analysis revealed abundant stress-related motifs, including abscisic acid (ABA) and methyl jasmonate (MeJA) response elements, suggesting roles in abiotic stress adaptation. Transcriptome and qRT-PCR data confirmed that AsNHX1/3/7/9/14/23/24/25/32 were up-regulated under salt stress, highlighting their importance in salinity tolerance.

conclusionsThis study provides the first comprehensive characterization of the AsNHX gene family, detailing their evolutionary, structural, and functional features. The findings offer critical insights into salt adaptation mechanisms in oat and identify promising targets for genetic improvement of salinity tolerance.

Indexed as

AvenaGene Expression ProfilingMultigene FamilyPlant ProteinsSodium-Hydrogen ExchangersGene Expression Regulation, PlantGenome, PlantPhylogenySalt ToleranceStress, PhysiologicalPlant ProteinsSodium-Hydrogen ExchangersAvena sativaNHX gene familyqRT-PCRSalt stress

Identifiers

PMID41612172
PMCPMC12922412

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LicenceCC BY
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.