SynthesisOral diseases2026
Platelet Levels Associated With Bleeding Risk for Dental Interventions: A Systematic Review.
Synthesis in Oral diseases, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Endodontic Management Before, During and After Head and Neck Radiotherapy: Biological, Diagnostic and Clinical Considerations in Head and Neck Cancer Patients.International endodontic journal · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo evaluate evidence in relation to postoperative bleeding in humans aged ≥ 16 with preoperative platelet counts < 50,000/μL, compared to those above, undergoing dental interventions.
methodsQuantitative synthesis without meta-analysis was conducted through an electronic search conducted on Ovid MEDLINE and Embase from 1946 to April 2024 with no restriction on study design. Primary outcome was postoperative bleeding in patients with platelet count < 50,000/μL due to dental interventions. Two reviewers assessed independently, and a third resolved conflicts. This study was reported according to PRISMA 2020 and registered on PROSPERO (CRD42024527279).
results1633 unique articles were identified. Six case reports, four case series, nine cohort studies and one trial fulfilled the inclusion. Overall, 983 included cases consisted of 968 oral surgery, 10 periodontology and 5 dental anaesthesia cases. Postoperative bleeding occurred in 65 cases following oral surgery procedures, of which 1 was life-threatening. Bleeding rates for cases with platelet levels < 50,000/μL were 12.9%, and 4.9% for ≥ 50,000/μL. Risk ratio was 2.95 (95% CI: 1.76-4.96; p < 0.0001).
conclusionsThere is no evidence that platelet counts < 50,000/μL is a contraindication for dental interventions, although findings suggest higher postoperative bleeding rates, particularly in oral surgery. Patients should be assessed individually, with more controlled trials required.
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Registered trials
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