Observational studyNeurosurgical review2026
Tailored vertebral artery mobilisation in complex craniovertebral junction surgery.
Observational study in Neurosurgical review, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
The surgical management of complex craniovertebral junction (CVJ) anomaly requires decompression of the neurovascular structures. Besides the atlantoaxial dislocation, the spectrum of anomalies noticed at CVJ is myriad. This includes an occipitalised C1 arch, hypoplasia of the C2 pedicle, basilar invagination, a high-riding vertebral artery (VA), a lower origin of the posterior inferior cerebellar artery (PICA), and unilateral or bilateral VA hypoplasia. The aberrant course of the VA has been the most challenging entity to access the C1-C2 joint. The atlantoaxial joint remodelling and reorientation play a vital role in achieving stability in this region. Here, we aim to describe the surgical nuances and share our experience with tailored VA mobilisation for the efficient management of CVJ anomalies. All cases of CVJ anomaly operated between January 2018 and December 2024 were included in this retrospective observational study. The clinical, radiological and operative details were collected from the neurosurgery record-keeping system. The surgical nuances and follow-up recovery of patients with VA anomaly (study group) were compared with those of patients having a normal course of VA (control group). Postoperative clinicoradiological improvement was evaluated at three-month follow-up visits. A total of 32 patients were analysed with a mean age of 47.21 ± 16.20 years. The median pre-operative Nurick's grade amongst the study population was 4 (IQR: 3,4 and Range: 3-5). Eighteen patients (18/32, 56.3%) underwent unilateral VA mobilisation (VAM), whereas fourteen patients (14/32, 43.7%) underwent bilateral VAM. After surgery, at the three-month follow-up visit, the median post-operative Nurick's grade was 3 (IQR: 2,3 and Range: 2-5), which was statistically significant (P = 0.002). The mean follow-up duration was 28.5 months (range: 6-85 ± 13.6 months) without any procedure-related mortality. Tailored VAM is an excellent surgical strategy for the management of complex CVJ pathology with an anomalous VA course. It provides a safe surgical corridor to access the C1-C2 joint without increasing the risk of injury to neurovascular structures.
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