Evidence map›Paper›PMID 41611867›Full record

ArticleNature immunology2026

CD38 endows local antigen-specific T

Hsin-Hsiang Chen, Sofia Tyystjärvi, Diego Ruiz Navarro, Ravi Kant, Tanja Groll, Ingrid Wagner, Helena Domínguez Moreno, Irene Bonafonte-Pardàs, Rupert Öllinger, Ali Maisam Afzali and 12 more

Abstract read
In one paragraph

Article in Nature immunology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors.

Hsin-Hsiang ChenInstitute for Experimental Neuroimmunology, Technical University of Munich School of Medicine, Munich, Germany.ORCID http://orcid.org/0000-0003-2496-0607
Sofia TyystjärviInstitute for Experimental Neuroimmunology, Technical University of Munich School of Medicine, Munich, Germany.ORCID http://orcid.org/0000-0002-5057-1923
Diego Ruiz NavarroInstitute for Experimental Neuroimmunology, Technical University of Munich School of Medicine, Munich, Germany.ORCID http://orcid.org/0009-0007-4825-8624
Ravi KantDepartment of Biotechnology and Bioinformatics, School of Life Sciences, University of Hyderabad, Hyderabad, India.
Tanja GrollInstitute of Pathology, Technical University of Munich, Munich, Germany.ORCID http://orcid.org/0000-0002-9049-9145
Ingrid WagnerDepartment of Pathology and Immunology, Division of Clinical Pathology, Geneva Faculty of Medicine, Centre Médical Universitaire, Geneva, Switzerland.ORCID http://orcid.org/0000-0003-4437-9799
Helena Domínguez MorenoInstitute for Experimental Neuroimmunology, Technical University of Munich School of Medicine, Munich, Germany.
Irene Bonafonte-PardàsInstitute for Computational Biology, Helmholtz Munich, Campus Neuherberg, Neuherberg, Germany.ORCID http://orcid.org/0009-0005-1053-1838
Rupert ÖllingerInstitute of Molecular Oncology and Functional Genomics, TranslaTUM Cancer Center, Technical University of Munich School of Medicine, Munich, Germany.ORCID http://orcid.org/0000-0002-2292-5982
Ali Maisam AfzaliInstitute for Experimental Neuroimmunology, Technical University of Munich School of Medicine, Munich, Germany.ORCID http://orcid.org/0000-0002-3256-5298
Sylvia HeinkInstitute for Experimental Neuroimmunology, Technical University of Munich School of Medicine, Munich, Germany.ORCID http://orcid.org/0000-0002-3276-6313
Lisa Charlotte RichterInstitute for Experimental Neuroimmunology, Technical University of Munich School of Medicine, Munich, Germany.ORCID http://orcid.org/0009-0007-1603-5055
Christopher SieInstitute for Experimental Neuroimmunology, Technical University of Munich School of Medicine, Munich, Germany.ORCID http://orcid.org/0000-0002-8066-7539
Gildas LepennetierInstitute for Experimental Neuroimmunology, Technical University of Munich School of Medicine, Munich, Germany.
Lea SeeholzerInstitute for Experimental Neuroimmunology, Technical University of Munich School of Medicine, Munich, Germany.ORCID http://orcid.org/0009-0004-3010-2910
Katja SteigerInstitute of Pathology, Technical University of Munich, Munich, Germany.ORCID http://orcid.org/0000-0002-7269-5433
Doron MerklerDepartment of Pathology and Immunology, Division of Clinical Pathology, Geneva Faculty of Medicine, Centre Médical Universitaire, Geneva, Switzerland.ORCID http://orcid.org/0000-0002-0247-2007
Roland RadInstitute of Molecular Oncology and Functional Genomics, TranslaTUM Cancer Center, Technical University of Munich School of Medicine, Munich, Germany.ORCID http://orcid.org/0000-0002-6849-9659
Gunnar SchottaDivision of Molecular Biology, Biomedical Center, Faculty of Medicine, LMU Munich, Martinsried, Germany.
Benjamin SchubertInstitute for Computational Biology, Helmholtz Munich, Campus Neuherberg, Neuherberg, Germany.ORCID http://orcid.org/0000-0003-3412-1102
Andreas MuschaweckhInstitute for Experimental Neuroimmunology, Technical University of Munich School of Medicine, Munich, Germany.ORCID http://orcid.org/0000-0002-6870-1378
Thomas KornInstitute for Experimental Neuroimmunology, Technical University of Munich School of Medicine, Munich, Germany. thomas.korn@tum.de.ORCID http://orcid.org/0000-0002-3633-0955

Funding

Deutsche Forschungsgemeinschaft (German Research Foundation) EXC 2145 (SyNergy, ID 390857198)Deutsche Forschungsgemeinschaft (German Research Foundation) GRK2668 (ID 435874434)Deutsche Forschungsgemeinschaft (German Research Foundation) TRR355 (ID 490846870)Gemeinnützige Hertie-Stiftung (Hertie Foundation) Network of Clinical Neuroscience
6 · The paper itself

Abstract

Foxp3-expressing regulatory T (T

Indexed as

ADP-ribosyl Cyclase 1Central Nervous SystemEncephalomyelitis, Autoimmune, ExperimentalMembrane GlycoproteinsT-Lymphocytes, RegulatoryAnimalsFemaleInflammationInterleukin-2MiceMice, Inbred C57BLMice, KnockoutReceptors, Interleukin-2ADP-ribosyl Cyclase 1Cd38 protein, mouseInterleukin-2Membrane GlycoproteinsReceptors, Interleukin-2

Identifiers

PMID41611867
PMCPMC12956604

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.