Trial reportScientific reports2026
Cardiovascular disease prevention by personalized health promotion considering educational attainment.
Trial report in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Self-Perceived Individual Health Responsibility Among Healthcare Workers: Associated Factors and Relationship with Preventive Behaviors-A Cross-Sectional Study.Healthcare (Basel, Switzerland) · 2026Article
- Lifestyle and Cardiovascular Risk Factors by Educational Attainment in a Mediterranean Setting: A Cross-Sectional Analysis of a Population-Based Sample.Global heart · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors.
Funding
Abstract
To examine whether educational attainment modifies the effectiveness of personalized lifestyle recommendations for improving cardiovascular risk factors. This post-hoc analysis used data from a population-based randomized controlled trial in Girona, Spain, including adults aged 35-74 years without cardiovascular disease at baseline. Participants (n = 759; 48.7% men) were randomized to an intervention group (n = 380), which received personalized recommendations on diet and physical activity, or a control group (n = 379), which received a standard report of baseline results. Changes in systolic and diastolic blood pressure, LDL cholesterol, and physical activity energy expenditure from baseline to 12 months were analyzed. Multivariable linear regression models adjusted for age included an interaction term defined as group × educational attainment × time (1 year) to assess effect modification. Analyses were stratified by sex. Among women in the intervention group, significant interactions by educational attainment were observed. Compared with women with lower educational attainment, those with higher attainment showed more favorable changes in diastolic blood pressure [beta-coefficient (95% confidence interval): - 1.98 (- 4.23; 0.27) vs. 1.63 (- 0.21; 3.48)], LDL cholesterol [- 4.61 (- 11.40; 2.18) vs. 5.71 (0.25; 11.17)], and physical activity energy expenditure [0.52 (0.04; 1.23) vs. - 0.01 (- 0.36; 0.26)]. No significant interactions were found among men in the intervention group or among participants in the control group. Overall, within-group changes in these outcomes did not reach statistical significance. Personalized lifestyle interventions may provide greater benefits for women with higher educational attainment, although overall improvements were modest.
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Registered trials
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