Evidence map›Paper›PMID 41611747›Full record

ArticleScientific reports2026

Relationship between right and left ventricle function in subjects free of cardiovascular diseases: a population-based MRI study.

Ricarda von Krüchten, Roberto Lorbeer, Susanne Rospleszcz, Annette Peters, Stefan Karrasch, Holger Schulz, Bernard E Bulwer, Charlotte Wintergerst, Esther Askani, Thierno D Diallo and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Ricarda von KrüchtenDepartment of Diagnostic and Interventional Radiology, Medical Center, Faculty of Medicine, University of Freiburg, Hugstetter Straße 55, 79106, Freiburg, Germany.
Roberto LorbeerDepartment of Radiology, University Hospital of Munich, Ludwig-Maximilians-University, Marchioninistraße 15, 81377, Munich, Germany.
Susanne RospleszczDepartment of Diagnostic and Interventional Radiology, Medical Center, Faculty of Medicine, University of Freiburg, Hugstetter Straße 55, 79106, Freiburg, Germany.
Annette PetersChair of Epidemiology, Institute for Medical Information Processing, Biometry and Epidemiology, Medical Faculty, Ludwig-Maximilians-University Munich, Marchioninistr. 15, 81377, Munich, Germany.
Stefan KarraschInstitute of Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, Ingolstädter Landstraße 1, 85764, Neuherberg, Germany.
Holger SchulzGerman Center for Diabetes Research (DZD), Partner Site Neuherberg, Ingolstädter Landstraße 1, 85764, Neuherberg, Germany.
Bernard E BulwerNoninvasive Cardiology - Echocardiography Department, Cardiovascular Division, Brigham and Women's Hospital, Boston, MA, USA.
Charlotte WintergerstDepartment of Diagnostic and Interventional Radiology, Medical Center, Faculty of Medicine, University of Freiburg, Hugstetter Straße 55, 79106, Freiburg, Germany.
Esther AskaniDepartment of Diagnostic and Interventional Radiology, Medical Center, Faculty of Medicine, University of Freiburg, Hugstetter Straße 55, 79106, Freiburg, Germany.
Thierno D DialloDepartment of Diagnostic and Interventional Radiology, Medical Center, Faculty of Medicine, University of Freiburg, Hugstetter Straße 55, 79106, Freiburg, Germany.
Fabian BambergDepartment of Diagnostic and Interventional Radiology, Medical Center, Faculty of Medicine, University of Freiburg, Hugstetter Straße 55, 79106, Freiburg, Germany.
Christopher L SchlettDepartment of Diagnostic and Interventional Radiology, Medical Center, Faculty of Medicine, University of Freiburg, Hugstetter Straße 55, 79106, Freiburg, Germany.
Blerim MujajDepartment of Diagnostic and Interventional Radiology, Medical Center, Faculty of Medicine, University of Freiburg, Hugstetter Straße 55, 79106, Freiburg, Germany. blerim.mujaj@gmail.com.ORCID http://orcid.org/0000-0001-5831-0800

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Right (RV) and left ventricular (LV) volumetric measurements by cardiac magnetic resonance imaging (MRI) are established for assessing systolic and diastolic function, but the role of MRI-derived lung volumes in LV function remains unclear. This study investigated the relationship between RV and LV function, considering lung volumes. In the KORA-MRI cohort, 361 subjects underwent 3 T whole-body MRI. Cardiac functional parameters were measured from cine-steady-state free precession sequences using cvi42. Lung volumes were derived semi-automatically with an in-house algorithm. Linear regression analyses assessed RV-LV relationships, adjusted for age, sex, cardiovascular risk factors, and lung volumes. Among 361 subjects (mean age 56.1 ± 9.1 years; 43% women), RV end-diastolic volume was positively associated with LV end-diastolic (β = 28.1, p < 0.001), end-systolic (β = 11.0, p < 0.001), and stroke volume (β = 17.0, p < 0.001), but inversely with ejection fraction (β = -1.4, p = 0.001). RV end-systole was positively associated with LV end-diastolic (β = 21.2, p < 0.001), end-systolic (β = 11.5, p < 0.001), stroke volume (β = 9.7, p < 0.001), and inversely with ejection fraction (β = -3.3, p < 0.001). Adjusting for lung volumes did not alter RV-LV associations, and no effect modification by sex was observed despite lung volume differences. In individuals without cardiovascular disease, RV and LV volumetric parameters were strongly associated, supporting the critical role of RV function in LV function, independent of lung volumes.

Indexed as

Cardiovascular DiseasesHeart VentriclesMagnetic Resonance ImagingVentricular Function, LeftVentricular Function, RightAgedFemaleHumansLungMagnetic Resonance Imaging, CineMaleMiddle AgedStroke VolumeCardiac functionCardiovascular imagingEpidemiologyLung volumesMagnetic resonance imaging

Identifiers

PMID41611747
PMCPMC12858920

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.