Evidence map›Paper›PMID 41611461›Full record

ArticleBMJ open2026

Understanding opioid use within the substance use journeys of adults receiving treatment: a qualitative study protocol of the participant-led timeline mapping approach.

Maria Jennifer Estrella, Samantha Wells, Rachel Foy, Lena Quilty, Nikki Bozinoff, Leslie Buckley, Stephen Lincoln, Sean Patenaude, Farihah Ali

Abstract read
In one paragraph

Article in BMJ open, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Maria Jennifer EstrellaInstitute for Mental Health Policy Research, Centre for Addiction and Mental Health, Toronto, Ontario, Canada jen.estrella@camh.ca.ORCID http://orcid.org/0000-0001-6398-0964
Samantha WellsInstitute for Mental Health Policy Research, Centre for Addiction and Mental Health, Toronto, Ontario, Canada.
Rachel FoyInstitute for Mental Health Policy Research, Centre for Addiction and Mental Health, Toronto, Ontario, Canada.
Lena QuiltyCampbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, Ontario, Canada.
Nikki BozinoffCampbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, Ontario, Canada.
Leslie BuckleyDepartment of Psychiatry, University of Toronto, Toronto, Ontario, Canada.
Stephen LincolnPatient and Family Experience, Centre for Addiction and Mental Health, Toronto, Ontario, Canada.
Sean PatenaudePatient and Family Experience, Centre for Addiction and Mental Health, Toronto, Ontario, Canada.
Farihah AliInstitute for Mental Health Policy Research, Centre for Addiction and Mental Health, Toronto, Ontario, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe opioid crisis remains a significant public health emergency. Key contributors to this crisis include an increasingly toxic drug supply and inadequate health policies that rely on strategies to address opioid-related harms and underutilise primary prevention and early intervention approaches. To inform comprehensive prevention and early intervention strategies, research is needed to explore pathways involving hazardous opioid use (ie, daily opioid use that results in, and may arise from, disruptions to health, relationships, work or social functioning) and the individual, social and structural factors that shape such pathways. This qualitative study aims to address this research gap by exploring the substance use journeys of adults with lived or living experiences of hazardous opioid use who are receiving substance use treatment at a large Canadian mental health hospital. METHODS AND ANALYSIS: A qualitative descriptive study informed by the life course perspective will be conducted. Data will be collected using participant-led timeline mapping in combination with semistructured interviews. Participants will include 20-30 adults who are receiving or have received substance use treatment from the hospital where the study is being conducted. Timelines and interviews will be analysed using thematic analysis. A brief demographic questionnaire will also be administered to describe characteristics of the sample. ETHICS AND DISSEMINATION: Ethical approval was granted on 1 October 2025 by the Centre for Addiction and Mental Health Research Ethics Board (Protocol no. 2025/026). Findings will be reported through peer-reviewed publications, lay language reports and/or academic conferences on mental health and substance use health research.

Indexed as

Opioid-Related DisordersAdultCanadaHumansInterviews as TopicQualitative ResearchResearch DesignSubstance-Related DisordersHealth policyMENTAL HEALTHPUBLIC HEALTHQUALITATIVE RESEARCHSubstance misuse

Identifiers

PMID41611461
PMCPMC12863319

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.