Evidence map›Paper›PMID 41610959›Full record

ArticleJournal of substance use and addiction treatment2026

Association between pregnancy intention and postpartum contraceptive interest among pregnant people with opioid use disorder.

Davida M Schiff, Alexindra Wheeler, Daniel Lewis, Mishka Terplan, Shelly F Greenfield, Jessica R Gray, Elizabeth E Krans, Marcela C Smid, Frankie Kropp, John T Winhusen

Abstract read
In one paragraph

Article in Journal of substance use and addiction treatment, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Davida M SchiffDivision of General Academic Pediatrics, Mass General for Children, Boston, MA, United States of America; Division of Newborn Medicine, Mass General for Children, Boston, MA, United States of America. Electronic address: davida.schiff@mgh.harvard.edu.
Alexindra WheelerDivision of General Academic Pediatrics, Mass General for Children, Boston, MA, United States of America.
Daniel LewisDepartment of Psychiatry & Behavioral Neuroscience, University of Cincinnati College of Medicine, Cincinnati, OH, United States of America.
Mishka TerplanFriends Research Institute, Baltimore, MD, United States of America.
Shelly F GreenfieldDivision of Women's Mental Health and Division of Alcohol, Drugs, and Addiction, McLean Hospital, 115 Mill St, Belmont, MA, 02478, United States of America; Harvard Medical School, 25 Shattuck Street, Boston, MA, 02115, United States of America.
Jessica R GrayProgram in Substance Use and Addiction Services, Massachusetts General Hospital, Boston, MA, United States of America.
Elizabeth E KransDepartment of Obstetrics and Gynecology, Magee-Womens Research Institute, University of Pittsburgh, Pittsburgh, PA, United States of America.
Marcela C SmidDepartment of Obstetrics and Gynecology, University of Utah Health, Salt Lake City, UT, United States of America.
Frankie KroppDepartment of Psychiatry & Behavioral Neuroscience, University of Cincinnati College of Medicine, Cincinnati, OH, United States of America.
John T WinhusenDepartment of Psychiatry & Behavioral Neuroscience, University of Cincinnati College of Medicine, Cincinnati, OH, United States of America; Center for Addiction Research, University of Cincinnati College of Medicine, 3230 Eden Ave, Cincinnati, OH, United States of America.

Funding

The National Drug Abuse Treatment Clinical Trials NetworkUG1DA015831 · NIDA · YALE UNIVERSITY · PI Gail D'Onofrio, Roger D. Weiss · 2015 to 2026
$110.8M
The Ohio Valley Node of the Clinical Trials Network (CTN-0153)UG1DA013732 · NIDA · UNIVERSITY OF CINCINNATI · PI T John WINHUSEN · 2015 to 2026
$42.5M
Greater Intermountain Node (CTN-0151)UG1DA049444 · NIDA · UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH · PI Gerald T. Cochran, Gerald T. Cochran · 2019 to 2026
$16.8M
Project-008UG1DA049436 · NIDA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Jane M. Liebschutz, Erin L Winstanley · 2019 to 2026
$10.5M
Improving Treatment Engagement and Adherence to Optimize Outcomes for Opioid-Exposed Mother-Infant DyadsK23DA048169 · NIDA · MASSACHUSETTS GENERAL HOSPITAL · PI SCHIFF, DAVIDA · 2019 to 2023
$998k
NIDA NIH HHS K23 DA048169NIDA NIH HHS UG1 DA013732NIDA NIH HHS UG1 DA015831NIDA NIH HHS UG1 DA049436NIDA NIH HHS UG1 DA049444
6 · The paper itself

Abstract

objectiveIdentify sociodemographic and substance use characteristics associated with pregnancy intention and explore the relationship between pregnancy intent and postpartum contraception interest among pregnant individuals with opioid use disorder (OUD).

methodsSecondary analysis of baseline data collected in the Medication Treatment for OUD in Expectant Mothers trial, which evaluated injectable versus sublingual buprenorphine. Current pregnancy intention was classified as "intended," "mistimed," "unwanted," or "ambivalent." Postpartum contraceptive interest was categorized into highly effective, effective, less effective, or none. Participant characteristics and contraceptive interest was compared across intention categories using Fisher's Exact and Kruskal-Wallis tests.

resultsOf 155 participants who completed baseline screening, 137 (88%) did not report any contraceptive use prior to their current pregnancy. Twenty-eight percent reported intended pregnancies, 27% mistimed, 15% never wanted, and 30% were ambivalent towards their current pregnancy. Individuals reporting intended pregnancies disclosed less substance use in the past ninety days and twelve months compared to other categories. Forty-seven percent of participants desired highly effective contraception after delivery, 28% desired effective contraception, 4% desired less effective contraception, and 21% did not desire any contraception. Participants reporting an unwanted pregnancy were significantly more interested in sterilization, while participants reporting a mistimed pregnancy were significantly more interested in a postpartum long-acting reversible contraception.

conclusionOur findings that individuals with intended pregnancies report less recent substance use suggests that reproductive health decision-making may be difficult to prioritize during periods of active addiction. In addition, the lack of association between pregnancy intention and postpartum contraceptive interest underscores a need for novel ways to support perinatal individuals with OUD in family planning conversations that honor their reproductive autonomy, values, and desires.

Indexed as

ContraceptionOpioid use disorderPregancy intentPregnancyReproductive health

Identifiers

PMID41610959
PMCPMC13204582

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.