Evidence map›Paper›PMID 41610847›Full record

ArticleCurrent biology : CB2026

Experience-dependent reconfiguration of thermoreceptors regulates neuronal response plasticity.

Nathan Harris, Priya Dutta, Nikhila Krishnan, Stephen Nurrish, Emily C Wilder, Piali Sengupta

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Current biology : CB, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Nathan HarrisDepartment of Biology, Brandeis University, 415 South Street, Waltham, MA 02454, USA. Electronic address: nharris70@gsu.edu.
Priya DuttaDepartment of Biology, Brandeis University, 415 South Street, Waltham, MA 02454, USA.
Nikhila KrishnanDepartment of Biology, Brandeis University, 415 South Street, Waltham, MA 02454, USA.
Stephen NurrishDepartment of Biology, Brandeis University, 415 South Street, Waltham, MA 02454, USA.
Emily C WilderNeuroscience Institute, Georgia State University, 100 Piedmont Avenue SE, Atlanta, GA 30303, USA.
Piali SenguptaDepartment of Biology, Brandeis University, 415 South Street, Waltham, MA 02454, USA. Electronic address: sengupta@brandeis.edu.

Funding

Mechanisms of sensory neuron morphological diversification, signaling, and functional plasticityR35GM122463 · NIGMS · BRANDEIS UNIVERSITY · PI Piali Sengupta · 2017 to 2026
$7.7M
Zeiss LSM 980 with Airyscan 2 for Imaging Core FacilityS10OD032336 · OD · GEORGIA STATE UNIVERSITY · PI CHEN, KUANGCAI · 2022 to 2022
$597k
Gene regulatory mechanisms underlying temperature-dependent neuronal plasticityF32NS112453 · NINDS · BRANDEIS UNIVERSITY · PI HARRIS, NATHAN CHRISTOPHER STEPHENSON · 2019 to 2021
$161k
NIGMS NIH HHS R35 GM122463NIH HHS S10 OD032336NINDS NIH HHS F32 NS112453
6 · The paper itself

Abstract

Neurons continuously adjust their properties as a function of experience. Precise modulation of neuronal responses is achieved by multiple cellular mechanisms that operate over a range of timescales. Primary sensory neurons not only rapidly adapt their sensitivities via posttranslational mechanisms, including regulated trafficking of sensory molecules,

Indexed as

Caenorhabditis elegansCaenorhabditis elegans ProteinsNeuronal PlasticitySensory Receptor CellsThermoreceptorsAnimalsCaenorhabditis elegans ProteinsAFDC. elegansguanylyl cyclaseplasticitythermoreceptortrafficking

Identifiers

PMID41610847
PMCPMC12866963

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.