Evidence map›Paper›PMID 41610821›Full record

ArticleClinical nutrition (Edinburgh, Scotland)2026

Dietary flavonoid intake and psychological well-being - A bidirectional relationship.

Alysha S Thompson, Nicola P Bondonno, Yan Lydia Liu, Farah Qureshi, Laura D Kubzansky, Claudia Trudel-Fitzgerald, Julia K Boehm, Eric B Rimm, Aedín Cassidy

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In one paragraph

Article in Clinical nutrition (Edinburgh, Scotland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Alysha S ThompsonCo-Centre for Sustainable Food Systems and The Institute for Global Food Security, Queen's University Belfast, Northern Ireland, UK.
Nicola P BondonnoCo-Centre for Sustainable Food Systems and The Institute for Global Food Security, Queen's University Belfast, Northern Ireland, UK; Danish Cancer Institute, Copenhagen, Denmark; Nutrition & Health Innovation Research Institute, School of Medical and Health Sciences, Edith Cowan University, Joondalup, WA, Australia.
Yan Lydia LiuDepartment Nutrition, Harvard T.H Chan School of Public Health, Boston, MA, USA.
Farah QureshiDepartment of Population, Family & Reproductive Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA; Department of Social and Behavioral Sciences, Harvard T.H. Chan School of Public Health, Boston, MA, USA; Lee Kum Sheung Center for Health and Happiness, Harvard T.H. Chan School of Public Health, Boston, MA, USA.
Laura D KubzanskyDepartment of Social and Behavioral Sciences, Harvard T.H. Chan School of Public Health, Boston, MA, USA.
Claudia Trudel-FitzgeraldLee Kum Sheung Center for Health and Happiness, Harvard T.H. Chan School of Public Health, Boston, MA, USA; Department of Psychology, Université du Québec à Trois-Rivières, Trois-Rivières, Quebec, Canada; Research Center, Institut Universitaire en Santé Mentale de Montréal, Montreal, Quebec, Canada.
Julia K BoehmDepartment of Psychology, Chapman University, Orange, CA, USA.
Eric B RimmDepartment Nutrition, Harvard T.H Chan School of Public Health, Boston, MA, USA; Channing Division of Network Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, USA.
Aedín CassidyCo-Centre for Sustainable Food Systems and The Institute for Global Food Security, Queen's University Belfast, Northern Ireland, UK. Electronic address: A.Cassidy@qub.ac.uk.

Funding

Long Term Multidisciplinary Study of Cancer in Women: The Nurses Health StudyUM1CA186107 · NCI · BRIGHAM AND WOMEN'S HOSPITAL · PI ELIASSEN, A. HEATHER, STAMPFER, MEIR · 2014 to 2023
$22.3M
NCI NIH HHS UM1 CA186107
6 · The paper itself

Abstract

BACKGROUND AND

aimHigher dietary flavonoid intake has been associated with lower risks of mortality and major chronic disease, yet its relationship with psychological well-being (PWB), a key contributor to health and quality of life, remains unclear. This study aimed to investigate bidirectional associations between dietary flavonoid intake and two PWB facets: happiness (positive emotional state) and optimism (generalized expectation of positive outcomes). Specifically, we examined whether (1) overall flavonoid-rich dietary patterns (flavodiet score), (2) intake of specific flavonoid-rich foods, and (3) total flavonoid and subclass intakes were each associated with happiness and optimism over time.

methodsData were drawn from the Nurses' Health Study to form two analytical samples. Flavonoid intake measured in 1990 (n = 44,659) was examined in relation to sustained happiness (1992-2000) while intake in 2002 (n = 36,723) was analysed in relation to sustained optimism (2004-2012). Secondary analyses assessed whether higher baseline levels of each PWB facet were associated with sustained higher flavonoid intake, over up to 18 years. Associations were assessed using generalized estimating equations, adjusting for potential confounders.

resultsHigher flavodiet scores were associated with a 3-6 % higher likelihood of sustained happiness [RR

conclusionsConsuming ∼3 servings/day of flavonoid-rich foods is associated with sustained PWB, and higher baseline PWB is associated with sustained higher flavonoid intake over up to 18 years. This bidirectional relationship suggests that integrated interventions targeting both diet and well-being may help promote long-term health and reduce chronic disease risk.

Indexed as

DietFlavonoidsPsychological Well-BeingAdultFemaleHappinessHumansMaleMiddle AgedOptimismQuality of LifeFlavonoidsFlavodiet scoreFlavonoid-rich foodsFlavonoidsHappinessOptimismPsychological well-being

Identifiers

PMID41610821
PMCPMC13352143

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.