Evidence map›Paper›PMID 41610630›Full record

ArticleAddictive behaviors2026

Passive data do not improve prediction or detection of alcohol consumption beyond temporal patterns in major depression: A 90-day cross-validated study.

Anna M Langener, Dawson Haddox, Daniel M Mackin, George D Price, Damien Lekkas, Amanda C Collins, Tess Z Griffin, Michael V Heinz, Matthew D Nemesure, Subigya Nepal and 3 more

Abstract readValidation Study
In one paragraph

Article in Addictive behaviors, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

13 authors.

Anna M LangenerCenter for Technology and Behavioral Health, Geisel School of Medicine, Dartmouth College, Lebanon, NH, United States. Electronic address: anna.m.langener@dartmouth.edu.
Dawson HaddoxDepartment of Psychology, University of Arizona, Tucson, AZ, United States.
Daniel M MackinDepartment of Psychiatry, Geisel School of Medicine, Dartmouth College, Lebanon, NH, United States.
George D PriceCenter for Technology and Behavioral Health, Geisel School of Medicine, Dartmouth College, Lebanon, NH, United States; Quantitative Biomedical Sciences Program, Dartmouth College, Lebanon, NH, United States.
Damien LekkasDepartment of Medical Social Sciences, Feinberg School of Medicine, Northwestern University, Chicago, IL, United States.
Amanda C CollinsDeparment of Psychiatry, Massachusetts General Hospital, Boston, MA, United States; Department of Psychiatry, Harvard Medical School, Boston, MA, United States.
Tess Z GriffinCenter for Technology and Behavioral Health, Geisel School of Medicine, Dartmouth College, Lebanon, NH, United States.
Michael V HeinzCenter for Technology and Behavioral Health, Geisel School of Medicine, Dartmouth College, Lebanon, NH, United States; Department of Psychiatry, Geisel School of Medicine, Dartmouth College, Lebanon, NH, United States.
Matthew D NemesureDigital Data Design Institute, Harvard Business School, Harvard University, Cambridge, MA, United States.
Subigya NepalStanford Institute for Human-Centered-AI, Stanford University, Palo Alto, CA, United States.
Arvind PillaiDepartment of Computer Science, Dartmouth College, Lebanon, NH, United States.
Andrew T CampbellCenter for Technology and Behavioral Health, Geisel School of Medicine, Dartmouth College, Lebanon, NH, United States; Department of Computer Science, Dartmouth College, Lebanon, NH, United States.
Nicholas C JacobsonCenter for Technology and Behavioral Health, Geisel School of Medicine, Dartmouth College, Lebanon, NH, United States; Department of Biomedical Data Science, Geisel School of Medicine, Dartmouth College, Lebanon, NH, United States.

Funding

Personalized Deep Learning Models of Rapid Changes in Major Depressive Disorder Symptoms using Passive Sensor Data from Smartphones and Wearable DevicesR01MH123482 · NIMH · DARTMOUTH COLLEGE · PI JACOBSON, NICHOLAS CHARLES · 2020 to 2024
$2.6M
NIMH NIH HHS R01 MH123482
6 · The paper itself

Abstract

Major Depressive Disorder (MDD) is one of the most prevalent psychological disorders and frequently co-occurs with alcohol use disorders, increasing the risk of functional impairment. Monitoring alcohol use during depression treatment is therefore critical for early intervention. Passively collected data via devices like smartphones and smartwatches, offers a low-burden method for monitoring behavior in real time. This study investigated whether deep learning models trained on passively collected data (i.e., accelerometer, heart rate, respiratory rate, screen usage, and GPS data) could detect and predict alcohol use in individuals with MDD. Data were collected from 300 clinically depressed individuals who were enrolled in the Tracking Depression Study, a 90-day longitudinal study. Participants self-reported their alcohol use every week by completing the Timeline FollowBack. We trained models to predict same-day and next-day alcohol use. To validate these models, we split the data by participant, so that predictions were made on individuals who were not included in the training set. The models achieved moderate performance (mean AUC = 0.67 for both prediction tasks) when capturing both interindividual (between-person) and intraindividual (within-person) variability. Similar performances were observed when evaluating the model exclusively on predicting intraindividual variability (AUCs = 0.69 same-day, 0.68 next-day). However, model performance remained comparable to a baseline using only the day of week as predictor. These findings suggest that much of the predictive signal derives from temporal patterns. This indicates that interventions aligned with such temporal cues may already be effective, and that the added value of our model appears limited.

Indexed as

Alcohol DrinkingDeep LearningMajor Depressive DisorderAdultFemaleHeart RateHumansLongitudinal StudiesMaleMiddle AgedPrediction AlgorithmsPredictive Learning ModelsSmartphoneAlcohol useDeep learningJITAIJust-in-time adaptive interventionsMajor depressive disorderMeta learnerPassive sensing

Identifiers

PMID41610630
PMCPMC13334849

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.