Evidence map›Paper›PMID 41610075›Full record

ArticleStereotactic and functional neurosurgery2026

Denial of Hardware-Related Skin Erosion in Patients with Effective Deep Brain Stimulation: A Novel Phenomenon.

Filipe Wolff Fernandes, Rasmus Stenmark Persson, Assel Saryyeva, Joachim Runge, Patric Blomstedt, Joachim K Krauss

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Article in Stereotactic and functional neurosurgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Filipe Wolff FernandesDepartment of Neurosurgery, Hannover Medical School, Hannover, Germany, wolfffernandes.filipe@mh-hannover.de.
Rasmus Stenmark PerssonDepartment of Clinical Science, University of Umeå, Umeå, Sweden.
Assel SaryyevaDepartment of Neurosurgery, Hannover Medical School, Hannover, Germany.
Joachim RungeDepartment of Neurosurgery, Hannover Medical School, Hannover, Germany.
Patric BlomstedtDepartment of Clinical Science, University of Umeå, Umeå, Sweden.
Joachim K KraussDepartment of Neurosurgery, Hannover Medical School, Hannover, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionDeep brain stimulation (DBS) is an established therapy that can significantly improve patients' quality of life in several disorders. Besides its benefits, hardware-related problems including erosion and wound infections are well known problems. In the present series, we describe a novel phenomenon manifesting as denial for hardware-related skin erosion in patients with movement disorders benefiting from DBS in various targets.

methodsPatients were collected from two large DBS cohorts over a period of 28 years. The skin erosion was identified upon the occasion of a routine follow-up with the patients apparently being unaware/not noticing its occurrence. Demographic, clinical, and operative data were analyzed. Additionally, the hardware-related skin erosion and its time of diagnosis, as well as the consecutive treatment, were registered.

resultsOverall, 5 patients were identified with denial for hardware-related skin erosion. Three were men; two were women. The mean age at surgery was 66 years (range, 54-78). Three patients had dystonia; 2 patients had Parkinson's disease. DBS targets were the globus pallidus internus and various thalamic nuclei. All patients benefited markedly from chronic DBS (mean improvement of 76.7% according to the specific rating scales). The hardware-related skin erosion was diagnosed at a median follow-up of 18 months after DBS implantation (range, 5-264 months). Despite multiple surgical attempts at preservation, the neurostimulation system was ultimately explanted in 3 patients.

conclusionDenial toward hardware-related skin erosion in DBS, most probably denial, is a rare but potentially serious complication during chronic DBS.

Indexed as

Deep brain stimulationDenialHardwareMovement disorders

Identifiers

PMID41610075
PMCPMC13038234

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