Evidence map›Paper›PMID 41609979›Full record

ArticleMolecular neurobiology2026

VKORC1L1 Downregulation Induced Vitamin K Cycle Disorder Exacerbates Neuronal Ferroptosis After Spinal Cord Injury.

Mingliang Tan, Chao Ma, Lingxia Min, Cheng Cheng, Jilan Wang, Zhou Feng, Jingming Hou

Abstract read
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In one paragraph

Article in Molecular neurobiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Mingliang TanDepartment of Rehabilitation, Southwest Hospital, Third Military Medical University (Army Medical University), No. 30, Gaotanyan Street, Chongqing, 400038, The People's Republic of China.
Chao MaDepartment of Rehabilitation, Southwest Hospital, Third Military Medical University (Army Medical University), No. 30, Gaotanyan Street, Chongqing, 400038, The People's Republic of China.
Lingxia MinDepartment of Rehabilitation, Southwest Hospital, Third Military Medical University (Army Medical University), No. 30, Gaotanyan Street, Chongqing, 400038, The People's Republic of China.
Cheng ChengDepartment of Rehabilitation, Southwest Hospital, Third Military Medical University (Army Medical University), No. 30, Gaotanyan Street, Chongqing, 400038, The People's Republic of China.
Jilan WangDepartment of Rehabilitation, Southwest Hospital, Third Military Medical University (Army Medical University), No. 30, Gaotanyan Street, Chongqing, 400038, The People's Republic of China.
Zhou FengDepartment of Rehabilitation, Southwest Hospital, Third Military Medical University (Army Medical University), No. 30, Gaotanyan Street, Chongqing, 400038, The People's Republic of China. fengzhou0406@tmmu.edu.cn.
Jingming HouDepartment of Rehabilitation, Southwest Hospital, Third Military Medical University (Army Medical University), No. 30, Gaotanyan Street, Chongqing, 400038, The People's Republic of China. jingminghou@tmmu.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ferroptosis contributes significantly to neuronal loss and functional decline after spinal cord injury (SCI). Emerging evidence links the vitamin K (VK) cycle to ferroptosis regulation, but its status and role in SCI remain unknown. Therefore, this study aims to elucidate the role and underlying mechanism of the VK cycle in neuronal ferroptosis post-SCI, thereby providing insights for developing novel therapeutic strategies. We quantified VK

Indexed as

Down-RegulationFerroptosisNeuronsSpinal Cord InjuriesVitamin K Epoxide ReductasesAnimalsRats, Sprague-DawleyRecovery of FunctionVitamin K 2Vitamin K 2Vitamin K Epoxide ReductasesFerroptosisSpinal cord injuryThe VK cycleVK2VKORC1L1

Identifiers

PMID41609979

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.