Evidence map›Paper›PMID 41609902›Full record

ReviewCurrent nutrition reports2026

B Vitamin Deficiencies and Associated Neuropathies.

Mauricio Alvarez, Santiago Poveda, Alejandra Cisneros, Diana Parra, Maria Luna, Oswaldo Rincón, Issac Guzman

Abstract readReview
In one paragraph

Review in Current nutrition reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Mauricio AlvarezEndocrinology Department, Hospital Militar Central, Transversal 3 C #49-02, Bogotá, Colombia. Mauricioalvarez613@gmail.com.
Santiago PovedaNeurology Program, Universidad Militar Nueva Granada, Bogotá, Colombia.
Alejandra CisnerosEndocrinology Program, Universidad Militar Nueva Granada, Bogotá, Colombia.
Diana ParraEndocrinology Program, Universidad Militar Nueva Granada, Bogotá, Colombia.
Maria LunaEndocrinology Program, Universidad Militar Nueva Granada, Bogotá, Colombia.
Oswaldo RincónEndocrinology Department, Hospital Militar Central, Transversal 3 C #49-02, Bogotá, Colombia.
Issac GuzmanEndocrinology Department, Hospital Militar Central, Transversal 3 C #49-02, Bogotá, Colombia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purpose of reviewThis review examines both historical and recent evidence to clarify the current understanding of the relationship between B vitamin deficiencies and neuropathies. RECENT

findingsVitamin B1 (thiamine) deficiency can lead to neurological disorders such as beriberi and Wernicke's encephalopathy, conditions with significant prevalence and mortality rates. Vitamin B12 (Cobalamin) is crucial for DNA synthesis, fatty acid metabolism, and myelin production, with its deficiency leading to neuropathies and cognitive disorders. Excess vitamin B6 (pyridoxine), rather than deficiency, appears to be associated with neuropathy. TAKEAWAYS/

conclusionsVitamin B1 and B12 deficiencies are linked to classic neuropathies, while the connection between vitamin B6 deficiency and neuropathy is less clear, though excess B6 is associated with neurotoxicity. Nutritional deficiencies are less common in developed countries but remain significant in developing nations. In developed countries, factors like alcohol consumption, bariatric surgery, and metformin use are increasing these deficiencies in clinical practice.

Indexed as

Nervous System DiseasesThiamine DeficiencyVitamin B 12 DeficiencyVitamin B DeficiencyWernicke EncephalopathyBeriberiHumansThiamineVitamin B 12Vitamin B 6 DeficiencyThiamineVitamin B 12BeriberiPyridoxineThiamine deficiencyVitamin B 12Wernicke encephalopathy

Identifiers

PMID41609902
PMCPMC12855320

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.