ArticlePediatric nephrology (Berlin, Germany)2026
Incidence and outcomes of stage 3 acute kidney injury in the setting of pediatric trauma: a trauma quality improvement program analysis.
Article in Pediatric nephrology (Berlin, Germany), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
backgroundAcute Kidney Injury (AKI) increases morbidity and mortality risk, yet data in pediatric trauma are limited. This study evaluated the incidence of Kidney Disease: Improving Global Outcomes (KDIGO) stage 3 AKI, kidney replacement therapy (KRT) use, and associated risk factors in pediatric trauma patients.
methodsPediatric patients (< 18 years) in the Trauma Quality Improvement Program (TQIP) database from 2017-2023 were analyzed for stage 3 AKI. Multivariable logistic regression (MVLR) identified associations between AKI and adverse outcomes, adjusting for confounders. Serious injury was defined as an abbreviated injury scale (AIS) ≥ 3 per body region.
resultsAmong 867,467 pediatric trauma cases, 510 developed stage 3 AKI. Compared to children without stage 3 AKI, affected children had higher median composite injury severity scores (4 versus 26, p < 0.001) and lower survival (98% versus 69%, p < 0.001). In the MVLR model, older children, male sex (OR 1.20, 95% CI: 0.97-1.49), serious injury to the head/neck (3.48, 2.84-4.28), thorax (2.50, 2.00-3.11), abdomen (5.90, 4.79-7.28), extremities (2.26, 1.84-2.79), and skin (3.16, 2.14-4.68), in-hospital cardiac arrest (8.18, 6.24-10.72), pulmonary embolism (3.88, 1.97-7.66), sepsis (36.32, 23.83-55.37), ventilator-associated pneumonia (3.10, 1.96-4.91), acute respiratory distress syndrome (1.73, 1.03-2.89), and extracorporeal support (9.34, 5.51-15.85) were associated with stage 3 AKI. Patients with urologic injuries had higher rates of stage 3 AKI (0.6% vs. 0.046%, p = 0.0001). KRT was used in 20% of stage 3 AKI cases.
conclusionsStage 3 AKI was rare in pediatric trauma but strongly linked to abdominal, head/neck, and urologic injuries. Mortality was markedly increased when stage 3 AKI occurred.
Indexed as
Identifiers
41609862What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.