Evidence map›Paper›PMID 41609818›Full record

ArticleSkeletal radiology2026

MRI surveillance for musculoskeletal sarcoma recurrence: is axial-only imaging good enough?

Arora Manasi, Ronnie A Sebro, Benjamin K Wilke, Hillary W Garner, Jeffrey J Peterson, Rupert O Stanborough

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Article in Skeletal radiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Arora ManasiDepartment of Radiology, Mayo Clinic, 4500 San Pablo Road, Jacksonville, FL, 32224, USA. arora.manasi@mayo.edu.
Ronnie A SebroDepartment of Radiology, Mayo Clinic, 4500 San Pablo Road, Jacksonville, FL, 32224, USA.
Benjamin K WilkeDepartment of Orthopedic Surgery, Mayo Clinic, 4500 San Pablo Road, Jacksonville, FL, 32224, USA.
Hillary W GarnerDepartment of Radiology, Mayo Clinic, 4500 San Pablo Road, Jacksonville, FL, 32224, USA.
Jeffrey J PetersonDepartment of Radiology, Mayo Clinic, 4500 San Pablo Road, Jacksonville, FL, 32224, USA.
Rupert O StanboroughDepartment of Radiology, Mayo Clinic, 4500 San Pablo Road, Jacksonville, FL, 32224, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe goal of this study is to compare the sensitivity, accuracy, and specificity of detection of musculoskeletal sarcoma local recurrence (LR) using axial-only MRI compared with multiplanar MRI. MATERIALS AND

methodsThis retrospective study included 101 patients (47 with pathology-proven LR, 54 without recurrence) who underwent pre- and post-operative MRIs between 2013 and 2023 at a single academic center. Three fellowship-trained musculoskeletal radiologists independently reviewed anonymized MRIs. Initial review included only the axial sequences from the surveillance MRIs. Secondary review following a 6-month washout included all sequences from the multiplanar surveillance MRIs.

resultsNo statistically significant differences in accuracy, sensitivity, and specificity were observed between axial-only and complete (multiplanar) MRI analyses (p > 0.05). Accuracy of LR detection with axial-only vs. complete (multiplanar) MRI was 94.5% vs. 93.1% (Reader 1), 87.1% vs. 91.1% (Reader 2), and 82.7% vs. 86.1% (Reader 3). LR size ranged from 0.7 to 8.9 cm (mean 3.2 cm, median 2.6 cm). All missed recurrences when using axial-only surveillance MRI measured < 2 cm. Inter-reader agreement improved from 0.768 (axial-only) to 0.834 (complete MRI).

conclusionSurveillance MRI using axial sequences alone demonstrated comparable accuracy, sensitivity, and specificity to multiplanar MRI for detecting musculoskeletal sarcoma LR.

Indexed as

Bone NeoplasmsMagnetic Resonance ImagingMuscle NeoplasmsNeoplasm Recurrence, LocalSarcomaAdultAgedFemaleHumansMaleMiddle AgedReproducibility of ResultsRetrospective StudiesSensitivity and SpecificityAxial and multiplanar MRILocal recurrenceMRI surveillanceSarcoma

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.