Evidence map›Paper›PMID 41609732›Full record

Observational studyThe American journal of occupational therapy : official publication of the American Occupational Therapy Association2026

Cognitive Impairments and Health System Outcomes in Inpatient Rehabilitation: A Comparison of Patients With Stroke and Those With Type II Diabetes Mellitus.

Jessica Edelstein, Bethany Rajaratnam, Audrey Rozell, William McCall, Hallie Zeleznik, Elizabeth Skidmore

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In one paragraph

Observational study in The American journal of occupational therapy : official publication of the American Occupational Therapy Association, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Jessica EdelsteinJessica Edelstein, PhD, OTR/L, is Research Scientist and Research Assistant Professor, Shirley Ryan AbilityLab and Department of Physical Medicine & Rehabilitation, Northwestern University, Chicago, IL; jedelstein@sralab.org.
Bethany RajaratnamBethany Rajaratnam, MS, CCC-SLP, is Speech-Language Pathologist, Duke Regional Hospital, Durham, NC.
Audrey RozellAudrey Rozell, MA, CCC-SLP, is Director of Rehabilitation Services, UPMC Rehabilitation Institute, UPMC McKeesport, Elizabeth, PA.
William McCallWilliam McCall, MPT, is former Director of Rehabilitation Services, UPMC Rehabilitation Institute, UPMC McKeesport, Monongahela, PA.
Hallie ZeleznikHallie Zeleznik, PT, DPT, is Visiting Associate Professor, Department of Physical Therapy, University of Pittsburgh, Pittsburgh, PA.
Elizabeth SkidmoreElizabeth Skidmore, PhD, OTR/L is Professor, Department of Occupational Therapy, School of Health and Rehabilitation Sciences, University of Pittsburgh, Pittsburgh, PA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

importanceCognitive impairment is associated with poor outcomes in inpatient rehabilitation (IPR) but may be underrecognized among patients without neurologic diagnoses.

objectiveTo compare cognitive impairment prevalence between IPR patients with ischemic stroke and patients with Type II diabetes mellitus (T2DM) without a cerebrovascular diagnosis and to examine associations with functional outcomes and readmissions.

designThis observational, cross-sectional study used retrospective electronic medical record data collected from 2019 to 2022.

settingSingle inpatient rehabilitation facility in an academic health system.

participantsThe sample consisted of 360 patients admitted to IPR, including 147 patients with ischemic stroke without T2DM and 213 patients with T2DM without a neurologic diagnosis. OUTCOMES AND MEASURES: Cognitive status was assessed at admission using the Montreal Cognitive Assessment (MoCA). Outcomes included discharge self-care and mobility (Section GG), within-stay readmission, and 30-day postdischarge readmission.

resultsMild cognitive impairment was more prevalent among patients with T2DM than among patients with stroke at admission. Patients with stroke had lower mean MoCA scores at admission and discharge. Diagnosis was not associated with discharge self-care, discharge mobility, or readmission outcomes. Higher admission functional status and lower disease burden were associated with better functional outcomes, and higher admission mobility was associated with lower odds of within-stay readmission. CONCLUSIONS AND RELEVANCE: Routine, diagnosis-agnostic cognitive screening identified high rates of cognitive impairment across diagnostic groups in IPR. Occupational therapy practitioners should incorporate systematic cognitive screening and follow-up functional cognition assessment to guide intervention planning and discharge preparation. Plain-Language Summary: Many people receiving inpatient rehabilitation experience problems with thinking and memory that can affect daily activities and recovery. These problems are often expected after stroke but may be overlooked in people with other health conditions, such as diabetes. This study compared cognitive impairment and rehabilitation outcomes in people with stroke and people with Type II diabetes who did not have a stroke. The study found that mild cognitive impairment was common in both groups, including many people with diabetes. Whether a person had a stroke or diabetes did not explain differences in functional outcomes or hospital readmissions. Instead, a person's functional ability at admission and overall health burden were more strongly related to outcomes. These findings suggest that occupational therapy practitioners should routinely screen cognition for all patients in inpatient rehabilitation, not only those with neurologic diagnoses. Early identification of cognitive challenges can support therapy planning, daily functioning, and safe discharge.

Indexed as

Cognitive DysfunctionDiabetes Mellitus, Type 2StrokeStroke RehabilitationAgedAged, 80 and overCross-Sectional StudiesFemaleHumansInpatientsMaleMiddle AgedOccupational TherapyPatient ReadmissionPrevalenceRetrospective Studies

Identifiers

PMID41609732
PMCPMC12955713

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.