Evidence map›Paper›PMID 41609668›Full record

ArticlePrion2026

Prion seeding activity in DNA extractions: implications for laboratory biosafety.

Sarah C Gresch, Tamara Morrill, Maddy Ellis-Cramer, Maria Arifin, Lexi E Frank, Jason C Bartz, Marc D Schwabenlander, Tiffany M Wolf, Gordon B Mitchell, Jiewen Guan and 1 more

Abstract read
In one paragraph

Article in Prion, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Sarah C GreschDepartment of Veterinary and Biomedical Sciences, College of Veterinary Medicine, University of Minnesota, St. Paul, MN, USA.
Tamara MorrillNational and World Organization for Animal Health Reference Laboratory for Scrapie and Chronic Wasting Disease, Canadian Food Inspection Agency, Ottawa, ON, Canada.
Maddy Ellis-CramerDepartment of Veterinary and Biomedical Sciences, College of Veterinary Medicine, University of Minnesota, St. Paul, MN, USA.
Maria ArifinNational and World Organization for Animal Health Reference Laboratory for Scrapie and Chronic Wasting Disease, Canadian Food Inspection Agency, Ottawa, ON, Canada.
Lexi E FrankDepartment of Veterinary and Biomedical Sciences, College of Veterinary Medicine, University of Minnesota, St. Paul, MN, USA.
Jason C BartzMinnesota Center for Prion Research and Outreach, College of Veterinary Medicine, University of Minnesota, St. Paul, MN, USA.ORCID 0000-0003-4081-7886
Marc D SchwabenlanderDepartment of Veterinary and Biomedical Sciences, College of Veterinary Medicine, University of Minnesota, St. Paul, MN, USA.ORCID 0000-0001-9664-6890
Tiffany M WolfMinnesota Center for Prion Research and Outreach, College of Veterinary Medicine, University of Minnesota, St. Paul, MN, USA.ORCID 0000-0003-1740-4442
Gordon B MitchellNational and World Organization for Animal Health Reference Laboratory for Scrapie and Chronic Wasting Disease, Canadian Food Inspection Agency, Ottawa, ON, Canada.
Jiewen GuanNational and World Organization for Animal Health Reference Laboratory for Scrapie and Chronic Wasting Disease, Canadian Food Inspection Agency, Ottawa, ON, Canada.ORCID 0000-0002-1322-6514
Peter A LarsenDepartment of Veterinary and Biomedical Sciences, College of Veterinary Medicine, University of Minnesota, St. Paul, MN, USA.ORCID 0000-0002-3634-3625

Funding

Minnesota Environment and Natural Resources Trust Fund
6 · The paper itself

Abstract

Infectious prions (PrP

Indexed as

Containment of BiohazardsDNALaboratoriesPrionsPrPSc ProteinsAnimalsBrainCricetinaeDeerEndopeptidase KMesocricetusWasting Disease, ChronicDNAEndopeptidase KPrionsPrPSc ProteinsBiosafetychronic wasting disease (CWD)DNA extractionInfectious prions (PrPSc)proteinase K (PK)real-time quaking-induced conversion (RT-QuIC)white-tailed deer (WTD)

Identifiers

PMID41609668
PMCPMC12867400

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.